Phosphine oxide, [(1E)-1-methyl-2-phenylethenyl]diphenyl-

Base Information

• Chemical Name: Phosphine oxide, [(1E)-1-methyl-2-phenylethenyl]diphenyl-
• CAS No.: 62556-17-6
• Molecular Formula: C21H19OP
• Molecular Weight: 318.355
• Mol file: 62556-17-6.mol

Synonyms:

Chemical Property of Phosphine oxide, [(1E)-1-methyl-2-phenylethenyl]diphenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phosphine oxide, [(1E)-1-methyl-2-phenylethenyl]diphenyl-

There total 14 articles about Phosphine oxide, [(1E)-1-methyl-2-phenylethenyl]diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1-Phenylprop-1-yne (673-32-5) + Diphenylphosphine oxide (4559-70-0) → (E)-diphenyl(1-phenylprop-1-en-2-yl)phosphine oxide (62556-17-6)

Guidance literature:

With pyridine; lanthanum tris(N,N-dimethylbenzylamine); at 20 ℃; for 48h; regioselective reaction; Glovebox; Inert atmosphere;

DOI:10.1021/acscatal.9b01538

Reference yield: 80.0%

E-methyl-1 phenyl-2 diphenylphosphino-1 ethylene (135219-14-6,107394-76-3) → (E)-diphenyl(1-phenylprop-1-en-2-yl)phosphine oxide (62556-17-6)

Guidance literature:

With dihydrogen peroxide; In ethanol; acetone; for 1.5h; Ambient temperature;

Reference yield:

1-Phenylprop-1-yne (673-32-5) + Diphenylphosphine oxide (4559-70-0) → (E)-diphenyl(1-phenylprop-1-en-2-yl)phosphine oxide (62556-17-6) + (Z)-1-phenyl-2-diphenylphosphinyl-1-propene

Guidance literature:

With Eosin Y; potassium carbonate; In water; for 24h; Overall yield = 45 %; diastereoselective reaction; Irradiation; Inert atmosphere;

DOI:10.1021/acscatal.8b02617

upstream raw materials:

(1RS,2SR)-1-phenyl-2-(diphenylphosphinoyl)propan-1-ol

E-methyl-1 phenyl-2 diphenylphosphino-1 ethylene

(E)-diphenyl(styryl)phosphine oxide

methyl iodide

Downstream raw materials:

diphenyl(1-phenylpropan-2-yl)phosphine oxide

Refernces

• 1、 Wang, Huamin,Li, Yongli,Tang, Zilu,Wang, Shengchun,Zhang, Heng,Cong, Hengjiang,Lei, Aiwen. "Z-Selective Addition of Diaryl Phosphine Oxides to Alkynes via Photoredox Catalysis". . p. 10599 - 10605. Retrieved 2018/10/25.
• 2、 Takaki, Ken,Komeyama, Kimihiro,Takehira, Katsuomi. "Synthesis of lanthanide(II)-imine complexes and their use in carbon-carbon and carbon-nitrogen unsaturated bond transformation". . p. 10381 - 10395. Retrieved 2007/10/03.