AF12198

Base Information

• Chemical Name: AF12198
• CAS No.: 185413-30-3
• Molecular Formula: C96H123N19O22
• Molecular Weight: 1895.1179
• Mol file: 185413-30-3.mol

Synonyms:AF12198;AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-AZE-TYR-ALA-LEU-PRO-LEU-NH2;AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-L-AZETIDINE-2-CARBONYL-TYR-ALA-LEU-PRO-LEU-NH2;AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-L-AZETIDINE-2-CARBOXYLIC ACID-TYR-ALA-LEU-PRO-LEU-NH2

Chemical Property of AF12198

Chemical Property:

• Appearance/Colour: solid
• PSA: 625.88000
• Density: 1.354 g/cm³
• LogP: 5.63910
• Storage Temp.: −20°C
• Solubility.: DMSO (Slightly), Methanol (Slightly), Water (Very Slightly)

Purity/Quality:

98%Min ^*data from raw suppliers

AF 12198 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: AF 12198 is a peptide that selectively binds Interleukin-1 (IL-1) receptor and blocks in vivo responses to IL-1 (1). The interleukin-1 receptor can activate the innate immune response by binding to cytokines (2). Dysregulation of cytokine production can lead to aberrant immune cells activation that could result in auto-inflammatory disorders.