8-(tetrahydro-2H-pyran-2-yloxy)octanal

Base Information

• Chemical Name: 8-(tetrahydro-2H-pyran-2-yloxy)octanal
• CAS No.: 57221-80-4
• Molecular Formula: C13H24O3
• Molecular Weight: 228.332
• Mol file: 57221-80-4.mol

Synonyms:

Chemical Property of 8-(tetrahydro-2H-pyran-2-yloxy)octanal

Chemical Property:

• Vapor Pressure: 0.000128mmHg at 25°C
• Boiling Point: 334.4°Cat760mmHg
• Flash Point: 147.1°C
• Density: 0.97g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 8-(tetrahydro-2H-pyran-2-yloxy)octanal

There total 13 articles about 8-(tetrahydro-2H-pyran-2-yloxy)octanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

8-(tetrahydro-2H-pyran-2-yloxy)octan-1-ol (51326-52-4) → 8-tetrahydropyranyloxyoctanal (57221-80-4)

Guidance literature:

With dipyridinium dichromate; In dichloromethane; at 20 ℃; for 20h;

DOI:10.1016/S0022-1139(02)00254-3

Reference yield: 85.0%

2-(8-nitrooctyloxy)tetrahydropyran → 8-tetrahydropyranyloxyoctanal (57221-80-4)

Guidance literature:

With potassium hydroxide; potassium permanganate; magnesium sulfate; In methanol; at 0 ℃; for 0.5h;

DOI:10.1080/00397919208019262

Reference yield: 22.0%

1,8-Octanediol (629-41-4) → 8-tetrahydropyranyloxyoctanal (57221-80-4)

Guidance literature:

DOI:10.1016/S0040-4020(01)90023-7

upstream raw materials:

8-(tetrahydro-2H-pyran-2-yloxy)octan-1-ol

1,8-Octanediol

3,4-dihydro-2H-pyran

8-nitrooctan-1-ol

Downstream raw materials:

10-methyl-1-undecanol

10-methylundecan-1-al

8-(tetrahydro-2'H-pyran-2'-yl-oxy)-1-octanoic acid

3-Hydroxy-10-(tetrahydro-pyran-2-yloxy)-2-(toluene-4-sulfonyloxymethyl)-decanoic acid methyl ester

Refernces

• 1、 -. "IDEBENONE COMPOUNDS". Page/Page column 51; 52. . Retrieved 2021/10/22.
• 2、 -. "DIHYDROOROTIC ACID DEHYDROGENASE INHIBITOR". Paragraph 0061; 0063; 0064. . Retrieved 2015/04/15.