1-Pyrrolidinecarboxylic acid, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenyl-, 1,1-dimethylethyl ester, (2S,4S)-

Base Information Edit

Chemical Name:1-Pyrrolidinecarboxylic acid, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenyl-, 1,1-dimethylethyl ester, (2S,4S)-
CAS No.:635724-49-1
Molecular Formula:C21H35NO3Si
Molecular Weight:377.599
Hs Code.:
Mol file:635724-49-1.mol

Synonyms:tert-butyl(2S,4S)-4-{[tert-butyl(dimethyl)silyl]oxy}-2-phenylpyrrolidine-1-carboxylate;(2S,4S)-tert-butyl 4-{[tert-butyl(dimethyl)silyl]oxy}-2-phenylpyrrolidine-1-carboxylate;(2S,4S)-4-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-2-PHENYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;

Suppliers and Price of 1-Pyrrolidinecarboxylic acid, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenyl-, 1,1-dimethylethyl ester, (2S,4S)-

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

American Custom Chemicals Corporation
(2S,4S)-4-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-2-PHENYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 95.00%
5MG
$ 503.33

Total 0 raw suppliers

Chemical Property of 1-Pyrrolidinecarboxylic acid, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenyl-, 1,1-dimethylethyl ester, (2S,4S)- Edit

Chemical Property:

PSA：38.77000
LogP:5.69680

Purity/Quality:: (2S,4S)-4-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-2-PHENYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-Pyrrolidinecarboxylic acid, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenyl-, 1,1-dimethylethyl ester, (2S,4S)-

There total 5 articles about 1-Pyrrolidinecarboxylic acid, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-phenyl-, 1,1-dimethylethyl ester, (2S,4S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 884902-55-0
(3S)-3-[(tert-butyldimethylsilyl)oxy]-4-chlorobutanenitrile

: 635724-49-1
tert-butyl (2S,4S)-4-{[tert-butyl(dimethyl)silyl]oxy}-2-phenylpyrrolidine-1-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran; various solvent(s) / 0 - 23 °C

2: H₂ / Pt/C

With hydrogen; platinum on activated charcoal; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2006.01.030

Reference yield:

: 56522-24-8
tert-butyldimethylsilyl cyanide

: 635724-49-1
tert-butyl (2S,4S)-4-{[tert-butyl(dimethyl)silyl]oxy}-2-phenylpyrrolidine-1-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: 95 percent / KCN; 18-C-6

2: tetrahydrofuran; various solvent(s) / 0 - 23 °C

3: H₂ / Pt/C

With potassium cyanide; 18-crown-6 ether; hydrogen; platinum on activated charcoal; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2006.01.030