γ-Methoxyisoeugenol

Base Information

• Chemical Name: γ-Methoxyisoeugenol
• CAS No.: 63644-71-3
• Molecular Formula: C11H14O3
• Molecular Weight: 194.23
• Mol file: 63644-71-3.mol

Synonyms:methylconiferyl ether;

Chemical Property of γ-Methoxyisoeugenol

Chemical Property:

• PSA: 38.69000
• LogP: 2.06040

Purity/Quality:

98% ^*data from raw suppliers

Gamma-Methoxyisoeugenol ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of γ-Methoxyisoeugenol

There total 11 articles about γ-Methoxyisoeugenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

methanol (67-56-1) + Acetic acid 2-methoxy-4-(1-methoxy-allyl)-phenyl ester (94930-69-5) → (E)-4-(3-methoxy-1-propenyl)-2-methoxyphenol (63644-71-3)

Guidance literature:

With potassium; for 1.5h; Heating;

Reference yield: 41.0%

4-allylguaiacol (97-53-0) → coniferaldehyde (20649-42-7,458-36-6) + 2-methoxy-4-(3-methoxy-1-propenyl)-phenol (63644-71-3) + vanillin (121-33-5,8014-42-4)

Guidance literature:

4-allylguaiacol; With sodium hydroxide; In methanol; at 20 ℃; for 0.166667h; Autoclave;

With oxygen; cobalt(II) diacetate tetrahydrate; In methanol; at 80 ℃; for 6h; under 380.026 Torr; Autoclave;

DOI:10.1002/jccs.201500357

Reference yield:

guaiacylglycerol-β-guaiacyl ether (7382-59-4) → 2-methoxy-4-propenylphenol (97-54-1) + 3-Guaiacylpropanol (2305-13-7) + coniferol (458-35-5) + 2-methoxy-4-(3-methoxy-1-propenyl)-phenol (63644-71-3) + 2-methoxy-phenol (90-05-1)

Guidance literature:

With Ni nanoparticles supported on framework ZIF-8; In methanol; at 200 ℃; for 8h; under 760.051 Torr; Inert atmosphere;

DOI:10.1039/c8gc03511c

upstream raw materials:

4-allylguaiacol

guaiacylglycerol-β-guaiacyl ether

coniferol

methanol

Downstream raw materials:

3-methoxy-4-hydroxybenzoic acid

vanillin

coniferaldehyde

Refernces

• 1、 Mao, Haifang,Wang, Lizhi,Zhao, Feifei,Wu, Jianxin,Huo, Haohua,Yu, Jun. "Cobalt-catalyzed Aerobic Oxidation of Eugenol to Vanillin and Vanillic Acid". . p. 261 - 266. Retrieved 2016/04/19.
• 2、 Kobayashi,Fujita,Mitsuhashi. "Studies on the constituents of umbelliferae plants. XV. Constituents of Cnidium officinale: Occurrence of pregnenolone, coniferylferulate and hydroxyphthalides". . p. 1427 - 1433. Retrieved 2007/10/02.