2-Nonynoic acid

Base Information

• Chemical Name: 2-Nonynoic acid
• CAS No.: 1846-70-4
• Molecular Formula: C9H14O2
• Molecular Weight: 154.209
• Hs Code.: 2916190090
• Mol file: 1846-70-4.mol

Synonyms:NSC 75864;non-2-ynoic acid;

Chemical Property of 2-Nonynoic acid

Chemical Property:

• Vapor Pressure: 0.0017mmHg at 25°C
• Melting Point: -5°C
• Refractive Index: 1.47
• Boiling Point: 272.3 °C at 760 mmHg
• Flash Point: 132.8 °C
• PSA: 37.30000
• Density: 0.994 g/cm³
• LogP: 2.04480

Purity/Quality:

98%,99%, ^*data from raw suppliers

Non-2-ynoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C

MSDS Files:

Total 1 MSDS from other Authors

Useful:

Technology Process of 2-Nonynoic acid

There total 12 articles about 2-Nonynoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

n-octyne (629-05-0) + carbon dioxide (124-38-9,18923-20-1) → non-2-ynoic acid (1846-70-4)

Guidance literature:

With 3-(1-mesityl-1H-imidazol-3-ium-3-yl)propane-1-sulfonate; caesium carbonate; potassium iodide; silver(l) oxide; In N,N-dimethyl-formamide; at 35 ℃; for 24h; under 750.075 Torr; Darkness;

DOI:10.1002/cctc.201601379

Reference yield: 98.0%

trimethyl(oct-1-yn-1-yl)silane (15719-55-8) + carbon dioxide (124-38-9,18923-20-1) → non-2-ynoic acid (1846-70-4)

Guidance literature:

trimethyl(oct-1-yn-1-yl)silane; carbon dioxide; With cesium fluoride; In dimethyl sulfoxide; at 20 ℃; for 3h; Schlenk technique;

With hydrogenchloride; In water; at 0 ℃; pH=> 1;

DOI:10.1039/c3ob40760h

Reference yield: 78.0%

n-octyne (629-05-0) + chloroformic acid ethyl ester (541-41-3) → non-2-ynoic acid (1846-70-4)

Guidance literature:

n-octyne; With n-butyllithium; In tetrahydrofuran; cyclohexane; at -78 ℃; for 0.5h; Inert atmosphere; Schlenk technique;

chloroformic acid ethyl ester; In tetrahydrofuran; at -78 ℃; for 0.833333h; Inert atmosphere; Schlenk technique;

With sodium hydroxide; In ethanol; at 20 ℃; for 2.5h; Inert atmosphere; Schlenk technique;

DOI:10.1039/d0ob01700k

upstream raw materials:

n-octyne

carbon dioxide

1,3-dilithio-oct-1-yne

1-methoxy-2-nonynyl phenyl sulfide

Downstream raw materials:

ethyl non-2-ynoate

2-methylheptanal

4-cyclohexyl-5-heptylidene-3-pentyloxazolidin-2-one

3-benzoyl-4-hydroxy-6-phenyl-2H-pyran-2-one

Refernces

• 1、 Li, Fa-Wang,Suo, Quan-Ling,Hong, Hai-Long,Zhu, Ning,Wang, Ya-Qi,Han, Li-Min. "DBU and copper(I) mediated carboxylation of terminal alkynes using supercritical CO2 as a reactant and solvent". . p. 3878 - 3880. Retrieved 2014.
• 2、 Hurst, Timothy E.,Deichert, Julie A.,Kapeniak, Lucas,Lee, Roland,Harris, Jesse,Jessop, Philip G.,Snieckus, Victor. "Sodium Methyl Carbonate as an Effective C1 Synthon. Synthesis of Carboxylic Acids, Benzophenones, and Unsymmetrical Ketones". supporting information. p. 3882 - 3885. Retrieved 2019/06/07.