Gaboxadol hydrochloride

Base Information

• Chemical Name: Gaboxadol hydrochloride
• CAS No.: 85118-33-8
• Molecular Formula: C6H9ClN2O2
• Molecular Weight: 176.6
• European Community (EC) Number: 285-687-7
• NSC Number: 759585
• UNII: 478RVH3TVD
• DSSTox Substance ID: DTXSID90234251
• Wikidata: Q27259031
• ChEMBL ID: CHEMBL1255746
• Mol file: 85118-33-8.mol

Synonyms:GABOXADOL HYDROCHLORIDE;THIP hydrochloride;85118-33-8;Gaboxadol (hydrochloride);Gaboxadol HCl;UNII-478RVH3TVD;478RVH3TVD;85118-33-8 (HCl);4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3-ol hydrochloride;4,5,6,7-Tetrahydroisoxazolo(5,4-c)pyridin-3(2H)-one monohydrochloride;EINECS 285-687-7;4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3(2H)-one hydrochloride;4,5,6,7-TETRAHYDROISOXAZOLO[5,4-C]PYRIDIN-3-OL HCL, GABOXADOL-HCL;Lu 02-030 (hydrochloride);THIP (hydrochloride);4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3(2H)-one monohydrochloride;SR-01000075651;4,5,6,7-Tetrahydro-isoxazolo[5,4-c]pyridin-3(2H)-one;4,5,6,7-Tetrahydroisoxazolo(5,4-c)pyridin-3(2H)-one hydrate;THIP HCl;(THIP);D00XNY;MLS002154080;SPECTRUM1503648;CHEMBL1255746;DTXSID90234251;HMS1571C05;Pharmakon1600-01503648;BCP16610;GABOXADOL HYDROCHLORIDE [MI];Tox21_501233;CCG-39368;MFCD00055180;NSC759585;AKOS024015212;LP01233;NCGC00094475-01;NCGC00094475-02;NCGC00094475-03;NCGC00094475-04;NCGC00261918-01;AS-53745;BP-12453;HY-10233;SMR000875361;J Med Chem 26: 895 (1983);CS-0002508;EU-0101233;G0405;T-101;EN300-152453;P17040;Gaboxadol hydrochloride, solid, >=98% (HPLC);SR-01000075651-1;SR-01000075651-3;SR-01000075651-6;SR-01000075651-7;4,5,6,7-tetrahydroisoxazolo-[5,4-c]-pyridin-3-ol;Q27259031;9-Oxa-3,8-Diazabicyclo[4.3.0]Non-10-En-7-one HCl;Z2688689710;4H,5H,6H,7H-[1,2]oxazolo[5,4-c]pyridin-3-ol hydrochloride;4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3(2H)-onehydrochloride;4,5,6,7-tetrahydro-[1,2]oxazolo[5,4-c]pyridin-3-one;hydrochloride;ISOXAZOLO(5,4-C)PYRIDIN-3(2H)-ONE, 4,5,6,7-TETRAHYDRO-, HYDROCHLORIDE (1:1);ISOXAZOLO(5,4-C)PYRIDIN-3(2H)-ONE, 4,5,6,7-TETRAHYDRO-, MONOHYDROCHLORIDE

Chemical Property of Gaboxadol hydrochloride

Chemical Property:

• Melting Point: 236 °C
• Boiling Point: 295.7 °C at 760 mmHg
• Flash Point: 132.6 °C
• PSA: 58.03000
• LogP: 0.74440
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: ethanol: soluble0.91mg/mL
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 176.0352552
• Heavy Atom Count: 11
• Complexity: 210

Purity/Quality:

99%, ^*data from raw suppliers

Gaboxadol hydrochloride ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CNCC2=C1C(=O)NO2.Cl
• Uses: GABAergic Agonist Gaboxadol is a sleep aid drug used for the treatment of chronic pain and insomnia. Gaboxadol is also known to exhibit antidepressant like properties through its agonistic activities towards GABA sites . Gaboxadol hydrochloride has been used in cell migration and invasion assay to assess liver cancer cell migration.