4,5-Dihydroxypentanoic acid

Base Information

• Chemical Name: 4,5-Dihydroxypentanoic acid
• CAS No.: 66679-29-6
• Molecular Formula: C5H10O4
• Molecular Weight: 134.132
• DSSTox Substance ID: DTXSID30523393
• Wikidata: Q82389449
• Mol file: 66679-29-6.mol

Synonyms:4,5-dihydroxypentanoic acid;66679-29-6;SCHEMBL326464;DTXSID30523393;AKOS006375457

Chemical Property of 4,5-Dihydroxypentanoic acid

Chemical Property:

• XLogP3: -1.2
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 134.05790880
• Heavy Atom Count: 9
• Complexity: 91

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CC(=O)O)C(CO)O

Technology Process of 4,5-Dihydroxypentanoic acid

There total 1 articles about 4,5-Dihydroxypentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pent-4-enoic acid (591-80-0) → 4,5-dihydroxypentanoic acid (66679-29-6) + succinic acid (110-15-6)

Guidance literature:

Reference yield:

4,5-dihydroxypentanoic acid (66679-29-6) → 5-hydroxymethyl-4,5-dihydrofuranone (10374-51-3)

Guidance literature:

Ansaeuern der alkal. Loesung;

Reference yield:

4,5-dihydroxypentanoic acid (66679-29-6) → 2-[4-(5,7-dimethoxy-4-oxo-3,4-dihydroquinazolin-2-yl)-2,6-dimethylphenoxy]ethyl 4,5-dinitroxypentanoate

Guidance literature:

Multi-step reaction with 2 steps

1: nitric acid; acetic acid / ethyl acetate / 2.17 h / 20 °C / Cooling with ice

2: benzotriazol-1-ol; dicyclohexyl-carbodiimide; dmap / tetrahydrofuran / 20 °C

With dmap; nitric acid; benzotriazol-1-ol; acetic acid; dicyclohexyl-carbodiimide; In tetrahydrofuran; ethyl acetate;

upstream raw materials:

pent-4-enoic acid

Downstream raw materials:

5-hydroxymethyl-4,5-dihydrofuranone