N,N'-Di-o-tolylformamidine

Base Information

• Chemical Name: N,N'-Di-o-tolylformamidine
• CAS No.: 16596-01-3
• Molecular Formula: C15H16 N2
• Molecular Weight: 224.305
• Hs Code.: 2925290090
• Mol file: 16596-01-3.mol

Synonyms:Formamidine,N,N'-di-o-tolyl- (6CI,8CI); N,N'-Bis(2-methylphenyl)formamidine;N,N'-Di-o-tolylformamidine; NSC 229470

Chemical Property of N,N'-Di-o-tolylformamidine

Chemical Property:

• Boiling Point: 356.7°Cat760mmHg
• Flash Point: 169.5°C
• PSA: 24.39000
• Density: 0.99g/cm³
• LogP: 4.14830

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-Di-o-tolylformamidine

There total 20 articles about N,N'-Di-o-tolylformamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

orthoformic acid triethyl ester (122-51-0) + o-toluidine (95-53-4) → N,N'-bis(2-methylphenyl)formamidine (16596-01-3)

Guidance literature:

With β‐cyclodextrin; In ethanol; water; at 20 ℃; for 12h; Catalytic behavior; Green chemistry;

DOI:10.1016/j.cclet.2012.08.003

Reference yield: 90.0%

acetic acid (64-19-7,77671-22-8) + o-toluidine (95-53-4) → N,N'-bis(2-methylphenyl)formamidine (16596-01-3)

Guidance literature:

With orthoformic acid triethyl ester; at 140 ℃;

DOI:10.1021/ol800628a

Reference yield: 89.0%

N,N-dimethyl-formamide (68-12-2,33513-42-7) + o-toluidine (95-53-4) → N,N'-bis(2-methylphenyl)formamidine (16596-01-3)

Guidance literature:

With sodium hydroxide; trimethylsilyl bromide; In dichloromethane; at 0 ℃;

upstream raw materials:

2'-methylformanilide

2-methylphenylthioformamide

orthoformic acid triethyl ester

o-toluidine

Downstream raw materials:

N-phenyl-N'-o-tolyl-formamidine

tris-(4-amino-3-methyl-phenyl)-methane

4-hydroxy-8-methyl-quinoline-3-carboxylic acid

4-isobutyl-3,5-dimethyl-2-[2-(2-methyl-anilino)-vinyl]-thiazolium; iodide

Refernces

• 1、 Roth, Torsten,Vasilenko, Vladislav,Wadepohl, Hubert,Wright, Dominic S.,Gade, Lutz H.. "Structures, Electronics, and Reactivity of Strained Phosphazane Cages: A Combined Experimental and Computational Study". supporting information. p. 7636 - 7644. Retrieved 2015/08/11.
• 2、 Tam, Annie,Armstrong, Ian S.,La Cruz, Thomas E.. "Multicomponent synthesis of 1-aryl 1,2,4-triazoles". supporting information. p. 3586 - 3589. Retrieved 2013/08/23.