Diethylphosphine oxide

Base Information

• Chemical Name: Diethylphosphine oxide
• CAS No.: 7215-33-0
• Molecular Formula: C4H11OP
• Molecular Weight: 106.104
• European Community (EC) Number: 815-258-7
• DSSTox Substance ID: DTXSID10457147
• Wikidata: Q82279882
• Mol file: 7215-33-0.mol

Synonyms:DIETHYLPHOSPHINE OXIDE;7215-33-0;diethyl(oxo)phosphanium;(ETHYLPHOSPHONOYL)ETHANE;Phosphine oxide, diethyl-;DIETHYLPHOSPHINEOXIDE;diethyl phosphine oxide;SCHEMBL1451;DTXSID10457147;GXXPZLPHLAKYLM-UHFFFAOYSA-N;MFCD02824570;AS-57809;FT-0701917;C77650;EN300-307510

Chemical Property of Diethylphosphine oxide

Chemical Property:

• Boiling Point: 52-53 °C(Press: 1.5 Torr)
• PSA: 40.54000
• Density: 0.9698 g/cm3
• LogP: 1.58590
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• Sensitive.: Moisture Sensitive
• XLogP3: -0.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 105.046926936
• Heavy Atom Count: 6
• Complexity: 45.5

Purity/Quality:

99% ^*data from raw suppliers

(ethylphosphonoyl)ethane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC[P+](=O)CC

Technology Process of Diethylphosphine oxide

There total 4 articles about Diethylphosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

C11H17OP → diethylphosphine oxide (7215-33-0) + benzyl(diethyl)phosphine oxide (4519-78-2)

Guidance literature:

With trimethylsilyl bromide; at 80 ℃; for 18h;

DOI:10.1021/ol0342913

Reference yield:

Diethyl(2,2,2,-trichloro-1-hydroxyethyl)phosphine oxide (2929-39-7) → dichloro-acetic acid (79-43-6) + diethylphosphine oxide (7215-33-0)

Guidance literature:

In ethanol; water; Kinetics; Rate constant; var. constant pH values; temp. dependency of velocity const.;

Reference yield:

→ diisopropyl hydroxymethylphosphonate (24630-68-0) + diethylphosphine oxide (7215-33-0)

Guidance literature:

upstream raw materials:

Diethyl(2,2,2,-trichloro-1-hydroxyethyl)phosphine oxide

diethylchlorophosphine

cyclohexanone

Downstream raw materials:

1-Diaethylphosphinyl-2-diphenyl-phosphinylaethan

C₁₉H₂₆O₂P₂

C₂₀H₂₈O₂P₂

α-(ethoxycarbonylamino)-benzyl-diethylphosphine oxide

Refernces

• 1、 -. "Phosphosulfonate herbicides". . . Retrieved 2008/06/13.
• 2、 Aksnes, Gunnar,Larsen, Rolf Olaf. "Kinetic Study of the Alkaline Hydrolysis of 2,2,2-Trichloro-1-hydroxyethyl Substituted Phosphinates and Phosphine Oxides". . p. 1967 - 1972. Retrieved 2007/10/02.