Piperidine, 1-hexyl-

Base Information

• Chemical Name: Piperidine, 1-hexyl-
• CAS No.: 7335-01-5
• Molecular Formula: C11H23N
• Molecular Weight: 169.31
• Mol file: 7335-01-5.mol

Synonyms:N-(1-hexyl)piperidine;1-hexyl-piperidine;N-hexylpiperidine;1-C6H13C5H10N;N-n-hexylpiperidine;hexylpiperidine;Piperidine,1-hexyl;Piperidine, 1-hexyl-;

Chemical Property of Piperidine, 1-hexyl-

Chemical Property:

• Refractive Index: 1.4522
• Boiling Point: 219.2°C
• PSA: 3.24000
• Density: 0.8292
• LogP: 2.99050

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Piperidine, 1-hexyl-

There total 7 articles about Piperidine, 1-hexyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.5%

piperidine (110-89-4) + 1-Pentyl-1-hexylamine (41495-45-8) → 1-pentylpiperidine (10324-58-0) + 1-hexylpiperidine (7335-01-5) + hexan-1-amine (111-26-2) + dihexylamine (143-16-8) + n-Pentylamine (110-58-7) + Di-n-amylamine (2050-92-2)

Guidance literature:

With hydrogen; sulphidized CoO-MoO₃; at 300 ℃; for 1h; under 45003.6 Torr; Mechanism; Product distribution;

Reference yield:

1-ethyl-piperidine (766-09-6) → 1-butyl-piperidine (4945-48-6) + 1-hexylpiperidine (7335-01-5)

Guidance literature:

With palladium/alumina; at 200 ℃; for 5h; under 3750.38 Torr; Inert atmosphere;

DOI:10.1039/c8ra08316a

Reference yield:

piperidine (110-89-4) + (E)-pent-2-ene (646-04-8) + carbon monoxide (201230-82-2) → 1-hexylpiperidine (7335-01-5) + N-methylcyclohexylamine (626-67-5) + 1-(2-ethyl-butyl)-piperidine (91249-15-9) + 2-methyl-1-pentylpiperidine

Guidance literature:

With hydrogen; bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; nixantphenoxaphos; In methanol; toluene; at 125 ℃; for 12h;

DOI:10.1002/chem.200600702

upstream raw materials:

piperidine

1-penten

carbon monoxide

1-Pentyl-1-hexylamine

Downstream raw materials:

3-n-hexylpyridine

piperidine

1-pentylpiperidine

1-Pentyl-1-hexylamine

Refernces

• 1、 Zhou, Yage,Wu, Dan,Hernández, Willinton Yesid,Ma, Changru,Su, Huangyang,Ordomsky, Vitaly. "Alkyl coupling in tertiary amines as analog of Guerbet condensation reaction". . p. 9845 - 9849. Retrieved 2019/04/01.
• 2、 Ahmed, Moballigh,Seayad, Abdul Majeed,Jackstell, Ralf,Beller, Matthias. "Amines made easily: A highly selective hydroaminomethylation of olefins". . p. 10311 - 10318. Retrieved 2007/10/03.