Octanoic acid, 2-hydroxy-, methyl ester

Base Information

• Chemical Name: Octanoic acid, 2-hydroxy-, methyl ester
• CAS No.: 73634-76-1
• Molecular Formula: C9H18O3
• Molecular Weight: 174.24
• Mol file: 73634-76-1.mol

Synonyms:

Chemical Property of Octanoic acid, 2-hydroxy-, methyl ester

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Octanoic acid, 2-hydroxy-, methyl ester

There total 15 articles about Octanoic acid, 2-hydroxy-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

methyl (E)-oct-2-enoate (7367-81-9) → 2-hydroxyoctanoic acid methyl ester (73634-76-1)

Guidance literature:

With phenylsilane; oxygen; bis(dipivaloylmethanato)manganese(II); In isopropyl alcohol; at 0 ℃; for 5h; under 760 Torr;

DOI:10.1246/cl.1990.1869

Reference yield: 67.0%

1,1,1-tris(methylthio)-2-octanol (124838-32-0) → 2-hydroxyoctanoic acid methyl ester (73634-76-1)

Guidance literature:

With mercury dichloride; mercury(II) oxide; In methanol; for 1h; Heating;

DOI:10.1246/bcsj.62.2013

Reference yield: 65.0%

5-pentyl-2-thioxo-[1,3]dioxolane-4-carboxylic acid methyl ester → 2-hydroxyoctanoic acid methyl ester (73634-76-1)

Guidance literature:

With magnesium; In methanol; for 0.833333h; Heating;

DOI:10.1080/00397919908086456

upstream raw materials:

diazomethane

2-hydroxy-octanoic acid

methanol

Octanoic acid

Downstream raw materials:

(E)-methyl oct-3-enoate

methyl (E)-oct-2-enoate

2-[4'-(2-benzyl-benzofuran-3-yl)-3,5-dibromo-biphenyl-4-yloxy]-octanoic acid methyl ester

methyl 2-bromooctanoate

Refernces

• 1、 Jenske, Ramona,Vetter, Walter. "Gas chromatography/electron-capture negative ion mass spectrometry for the quantitative determination of 2- and 3-hydroxy fatty acids in bovine milk fat". experimental part. p. 5500 - 5505. Retrieved 2010/03/25.
• 2、 Rozen,Ben-David. "BrF3, an underutilized reagent in organic chemistry: A novel C-C-N to C-N-C rearrangement". . p. 496 - 500. Retrieved 2007/10/03.