2,3,5-Trihydroxybenzaldehyde

Base Information

• Chemical Name: 2,3,5-Trihydroxybenzaldehyde
• CAS No.: 74186-01-9
• Molecular Formula: C₇H₆O₄
• Molecular Weight: 154.122
• DSSTox Substance ID: DTXSID40431430
• Wikidata: Q82245301
• Mol file: 74186-01-9.mol

Synonyms:2,3,5-trihydroxybenzaldehyde;74186-01-9;Benzaldehyde, 2,3,5-trihydroxy-;SCHEMBL1003422;DTXSID40431430

Chemical Property of 2,3,5-Trihydroxybenzaldehyde

Chemical Property:

• PSA: 77.76000
• LogP: 0.61590
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 154.02660867
• Heavy Atom Count: 11
• Complexity: 147

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=C(C(=C1C=O)O)O)O

Technology Process of 2,3,5-Trihydroxybenzaldehyde

There total 6 articles about 2,3,5-Trihydroxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-dihydroxybenzaldehyde (26153-38-8) → 2,3,5‐trihydroxybenzaldehyde (74186-01-9)

Guidance literature:

With sodium hydroxide; dipotassium peroxodisulfate;

Reference yield:

2,3,5-triacetoxy-benzaldehyde → 2,3,5‐trihydroxybenzaldehyde (74186-01-9)

Guidance literature:

With methanol; hydrogen; potassium acetate; anschliessend Behandeln der Reaktionsloesung mit wss. H₂SO₄;

Reference yield:

3,5-Dihydroxybenzoic acid (99-10-5) → 2,3,5‐trihydroxybenzaldehyde (74186-01-9)

Guidance literature:

Multi-step reaction with 5 steps

1: K₂S₂O₈; aqueous NaOH

2: sodium acetate

3: SOCl₂

4: palladium/BaSO₄; xylene / Hydrogenation

5: potassium acetate; methanol; hydrogen / anschliessend Behandeln der Reaktionsloesung mit wss. H₂SO₄

With methanol; sodium hydroxide; dipotassium peroxodisulfate; Pd-BaSO₄; thionyl chloride; hydrogen; potassium acetate; sodium acetate; xylene;

upstream raw materials:

3,5-dihydroxybenzaldehyde

3,5-Dihydroxybenzoic acid

2,3,5-trihydroxybenzoic acid

2,3,5-triacetoxy-benzoyl chloride