Sodium (2R,3R,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexyl phosphate

Base Information

• Chemical Name: Sodium (2R,3R,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexyl phosphate
• CAS No.: 54010-71-8
• Deprecated CAS: 140195-08-0
• Molecular Formula: C6H13 O9 P . Na
• Molecular Weight: 282.12
• Hs Code.: 29400000
• European Community (EC) Number: 222-938-1,258-921-0
• DSSTox Substance ID: DTXSID501014631
• Nikkaji Number: J205.585F
• Mol file: 54010-71-8.mol

Synonyms:3671-99-6;D-Glucose-6-phosphate disodium salt;Sodium (2R,3R,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexyl phosphate;d-glucose 6-phosphate disodium salt;G-6-P-Na2;D-Glucose 6-(disodium phosphate);disodium;[(2R,3R,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexyl] phosphate;D-Glucose 6-phosphate (sodium);glucose 6-phosphate sodium salt;54010-71-8;Glucose-6-phosphate disodium;SCHEMBL48152;disodium D-glucose-6-phosphate;DTXSID501014631;MFCD00136037;MFCD00150940;AKOS016009743;CCG-267507;GS-6271;26117-86-6 (.xH2O);H10152;A874294;disodium (2R,3S,4R,5R)-2,3,4,5-tetrahydroxy-6-(phosphonooxy)hexanal

Chemical Property of Sodium (2R,3R,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexyl phosphate

Chemical Property:

• Appearance/Colour: White crystalline solid
• Vapor Pressure: 1.1E-20mmHg at 25°C
• Melting Point: 204 °C (dec.)(lit.)
• Boiling Point: 667.8°Cat760mmHg
• Flash Point: 357.7°C
• PSA: 169.55000
• Density: g/cm³
• LogP: -2.66620
• Storage Temp.: 2-8°C
• Solubility.: H2O: 50 mg/mL, clear, colorless to very faintly yellow
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 6
• Exact Mass: 303.99360749
• Heavy Atom Count: 18
• Complexity: 251

Purity/Quality:

98%, ^*data from raw suppliers

RobisonEsterMonosodiumSalt ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C(C(C(C(C=O)O)O)O)O)OP(=O)([O-])[O-].[Na+].[Na+]
• Isomeric SMILES: C([C@H]([C@H]([C@@H]([C@H](C=O)O)O)O)O)OP(=O)([O-])[O-].[Na+].[Na+]
• Description: D-Glucose-6-phosphate is formed in cells when glucose is phosphorylated by hexokinase (or glucokinase) or by the conversion of glucose-1-phosphate by phosphoglucomutase, which is the first step of glycogen synthesis. It is stored as glycogen when blood glucose levels are high. Disruption of D-glucose-6-phosphate activity leads to glycogen storage disease type I or von Gierke’s disease, a group of inherited metabolic diseases characterized by severe hypoglycemia, growth retardation, and hepatomegaly, due to accumulation of glycogen and fat in the liver. D-Glucose-6-phosphate is also the starting molecule of both glycolysis and the pentose phosphate pathways. Because cancer cells adopt glycolysis as a major source of metabolic energy production, and the pentose phosphate pathway plays a role in helping glycolytic cancer cells to meet their anabolic demands, this compound can be used to study the progression of this process.