Benzenamine, 4-[4,5-dihydro-1-phenyl-3-[4-[(2-thienylmethylene)amino]phenyl]-1H-pyr azol-5-yl]-N,N-dimethyl-

Base Information

• Chemical Name: Benzenamine, 4-[4,5-dihydro-1-phenyl-3-[4-[(2-thienylmethylene)amino]phenyl]-1H-pyr azol-5-yl]-N,N-dimethyl-
• CAS No.: 77374-11-9
• Molecular Formula: C₂₈H₂₆N₄S
• Molecular Weight: 450.607
• Mol file: 77374-11-9.mol

Synonyms:

Chemical Property of Benzenamine, 4-[4,5-dihydro-1-phenyl-3-[4-[(2-thienylmethylene)amino]phenyl]-1H-pyr azol-5-yl]-N,N-dimethyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenamine, 4-[4,5-dihydro-1-phenyl-3-[4-[(2-thienylmethylene)amino]phenyl]-1H-pyr azol-5-yl]-N,N-dimethyl-

There total 4 articles about Benzenamine, 4-[4,5-dihydro-1-phenyl-3-[4-[(2-thienylmethylene)amino]phenyl]-1H-pyr azol-5-yl]-N,N-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

(E)-3-(4-Dimethylamino-phenyl)-1-(4-{[1-thiophen-2-yl-meth-(E)-ylidene]-amino}-phenyl)-propenone (77373-99-0) + phenylhydrazine (100-63-0) → C28H26N4S (77374-11-9)

Guidance literature:

With piperidine; In ethanol; for 5h; Heating;

Reference yield:

thiophene-2-carbaldehyde (98-03-3) → C28H26N4S (77374-11-9)

Guidance literature:

Multi-step reaction with 3 steps

1: ethanol / 3 h / Ambient temperature

2: 1)NaOH, C₂H₅OH / 1) 0 deg C 2) 15 to 25 deg C, 3h

3: 35 percent / piperidine / ethanol / 5 h / Heating

With piperidine; sodium hydroxide; ethanol; In ethanol;

Reference yield:

p-(2'-Thenylideneamino)acetophenone (77373-95-6) → C28H26N4S (77374-11-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1)NaOH, C₂H₅OH / 1) 0 deg C 2) 15 to 25 deg C, 3h

2: 35 percent / piperidine / ethanol / 5 h / Heating

With piperidine; sodium hydroxide; ethanol; In ethanol;

upstream raw materials:

(E)-3-(4-Dimethylamino-phenyl)-1-(4-{[1-thiophen-2-yl-meth-(E)-ylidene]-amino}-phenyl)-propenone

phenylhydrazine

thiophene-2-carbaldehyde

p-(2'-Thenylideneamino)acetophenone

Downstream raw materials:

3-Chloro-1-{4-[5-(4-dimethylamino-phenyl)-1-phenyl-4,5-dihydro-1H-pyrazol-3-yl]-phenyl}-4-thiophen-2-yl-azetidin-2-one

3-{4-[5-(4-Dimethylamino-phenyl)-1-phenyl-4,5-dihydro-1H-pyrazol-3-yl]-phenyl}-2-thiophen-2-yl-thiazolidin-4-one

Refernces