7-PHENYL-1-HEPTANOL

Base Information

• Chemical Name: 7-PHENYL-1-HEPTANOL
• CAS No.: 3208-25-1
• Molecular Formula: C13H20 O
• Molecular Weight: 192.301
• Hs Code.: 2906299090
• Mol file: 3208-25-1.mol

Synonyms:1-Heptanol,7-phenyl- (6CI,7CI,8CI); 7-Phenyl-1-heptanol; 7-Phenylheptanol; 7-Phenylheptylalcohol

Chemical Property of 7-PHENYL-1-HEPTANOL

Chemical Property:

• Appearance/Colour: colourless liquid
• Vapor Pressure: 0.000293mmHg at 25°C
• Refractive Index: 1.5080
• Boiling Point: 308.5°Cat760mmHg
• PKA: 15.19±0.10(Predicted)
• Flash Point: 125.1°C
• PSA: 20.23000
• Density: 0.95g/cm³
• LogP: 3.17190

Purity/Quality:

98%Min ^*data from raw suppliers

7-Phenylheptan-1-ol ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-PHENYL-1-HEPTANOL

There total 22 articles about 7-PHENYL-1-HEPTANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(Z)-1-Benzyloxy-7-phenylhept-6-ene (133839-57-3) → 7-phenylheptan-1-ol (3208-25-1)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; for 24h; under 2942.03 Torr; Ambient temperature;

DOI:10.1248/cpb.39.18

Reference yield: 92.99%

7-phenylheptanoic acid (40228-90-8) → 7-phenylheptan-1-ol (3208-25-1)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 4h;

Reference yield: 82.0%

7-phenyl-1-<<(1,1-dimethylethyl)dimethylsilyl>oxy>heptane (213379-60-3) → 7-phenylheptan-1-ol (3208-25-1)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; 0 deg C to rt, rt, 17 h;

DOI:10.1021/jo981617q

upstream raw materials:

7-phenylheptanoic acid methyl ester

ethylmagnesium bromide

1-chloro-3-hydroxypropane

3-(furan-1-yl)-1-phenyl-prop-2-en-1-one

Downstream raw materials:

1-bromo-7-phenyl-heptane

1-chloro-7-phenylheptane

(E)-1-(2-Benzyloxy-6-hydroxyphenyl)-9-phenyl-2-nonen-1-one

1-(2-Benzyloxy-6-hydroxyphenyl)-3-hydroxy-9-phenylnonan-1-one

Refernces

• 1、 Meka, Bharani,Ravada, Suryachandra Rao,Kancharla, Harikrishna,Golakoti, Trimurtulu. "Synthesis and biological evaluation of some undecanone derivatives". . p. 3106 - 3124. Retrieved 2017/10/06.
• 2、 Ponzano, Stefano,Berteotti, Anna,Petracca, Rita,Vitale, Romina,Mengatto, Luisa,Bandiera, Tiziano,Cavalli, Andrea,Piomelli, Daniele,Bertozzi, Fabio,Bottegoni, Giovanni. "Synthesis, biological evaluation, and 3D QSAR study of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters as N -acylethanolamine acid amidase (NAAA) inhibitors". supporting information. p. 10101 - 10111. Retrieved 2015/02/02.