3-(5-Bromofuran-2-yl)prop-2-ynoic acid

Base Information

• Chemical Name: 3-(5-Bromofuran-2-yl)prop-2-ynoic acid
• CAS No.: 3199-47-1
• Molecular Formula: C₇H₃BrO₃
• Molecular Weight: 215.003
• NSC Number: 203067
• DSSTox Substance ID: DTXSID20308318
• Wikidata: Q82056127
• Mol file: 3199-47-1.mol

Synonyms:3199-47-1;3-(5-bromofuran-2-yl)prop-2-ynoic acid;NSC203067;DTXSID20308318;AKOS013857591;NSC-203067

Chemical Property of 3-(5-Bromofuran-2-yl)prop-2-ynoic acid

Chemical Property:

• Vapor Pressure: 4.64E-05mmHg at 25°C
• Boiling Point: 335.7°Cat760mmHg
• Flash Point: 156.8°C
• Density: 1.9g/cm³
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 213.92656
• Heavy Atom Count: 11
• Complexity: 224

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(OC(=C1)Br)C#CC(=O)O

Technology Process of 3-(5-Bromofuran-2-yl)prop-2-ynoic acid

There total 6 articles about 3-(5-Bromofuran-2-yl)prop-2-ynoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (5-bromo-[2]furyl)-propiolic acid (3199-47-1)

Guidance literature:

With potassium hydroxide;

DOI:10.1021/ja01362a040

Reference yield:

2-bromo-3t-(5-bromo-[2]furyl)-acrylic acid ethyl ester (6824-30-2) → (5-bromo-[2]furyl)-propiolic acid (3199-47-1)

Guidance literature:

With potassium hydroxide;

Reference yield:

2-bromo-3t-(5-bromo-[2]furyl)-acryloyl chloride → (5-bromo-[2]furyl)-propiolic acid (3199-47-1)

Guidance literature:

at 70 - 80 ℃;

DOI:10.1021/ja01362a040

upstream raw materials:

2-bromo-3t-(5-bromo-[2]furyl)-acrylic acid ethyl ester

2-bromo-3t-(5-bromo-[2]furyl)-acrylic acid

5-bromo-2-furancarboxaldehyde

Downstream raw materials:

2-bromo-5-ethynylfuran

1-(5-bromofuran-2-yl)ethanone

3-(2'-furfuryl)propiolic acid