2-Propen-1-one, 3-(1-naphthalenyl)-1-phenyl-, (E)-

Base Information

• Chemical Name: 2-Propen-1-one, 3-(1-naphthalenyl)-1-phenyl-, (E)-
• CAS No.: 80674-36-8
• Molecular Formula: C₁₉H₁₄O
• Molecular Weight: 258.32
• Mol file: 80674-36-8.mol

Synonyms:α-naphthylchalcone;3-naphthalen-1-yl-1-phenyl-propenone;α-Naphthyliden-acetophenon;α-[Naphthyliden-(1)]-acetophenon;Phenyl-(2-[1]naphthyl-vinyl)-keton;[2-(α-Naphthyl)-vinyl]-phenyl-keton;

Chemical Property of 2-Propen-1-one, 3-(1-naphthalenyl)-1-phenyl-, (E)-

Chemical Property:

• PSA: 17.07000
• LogP: 4.73590

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Propen-1-one, 3-(1-naphthalenyl)-1-phenyl-, (E)-

There total 21 articles about 2-Propen-1-one, 3-(1-naphthalenyl)-1-phenyl-, (E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-naphthaldehyde (66-77-3) + acetophenone (98-86-2) → (E)-3-(naphthalen-1-yl)-1-phenylprop-2-en-1-one (42299-49-0,80674-36-8)

Guidance literature:

With potassium hydroxide; In ethanol; for 0.2h; Ambient temperature;

Reference yield: 94.0%

1-naphthalene methanol (4780-79-4) + acetophenone (98-86-2) → 3-(naphthalen-1-yl)-1-phenylprop-2-en-1-one (80674-36-8,42299-49-0)

Guidance literature:

With oxygen; caesium carbonate; In acetonitrile; at 20 ℃; for 24h; chemoselective reaction;

DOI:10.1016/j.mcat.2021.111516

Reference yield: 87.0%

1-naphthaldehyde (66-77-3) + acetophenone (98-86-2) → 3-(naphthalen-1-yl)-1-phenylprop-2-en-1-one (80674-36-8,42299-49-0)

Guidance literature:

With sodium hydroxide; In ethanol; for 4h; ice-salt bath;

upstream raw materials:

1-naphthaldehyde

acetophenone

benzonitrile

acetonitrile

Downstream raw materials:

3-(naphthalen-1-yl)-1-phenylpropan-1-one

2-methoxy-4-(1-naphthyl)-6-phenylpyridine-3-carbonitrile

Refernces

• 1、 Zhu, Guanxin,Duan, Zheng-Chao,Zhu, Haiyan,Qi, Minghui,Wang, Dawei. "Iridium and copper supported on silicon dioxide as chemoselective catalysts for dehydrogenation and borrowing hydrogen reactions". . . Retrieved 2021/04/02.
• 2、 Ramkumar, Sowmya,Nalini,Quraishi, Mumtaz A.,Ebenso, Eno E.,Verma, Chandrabhan. "Anti-corrosive property of bioinspired environmental benign imidazole and isoxazoline heterocyclics: A cumulative studies of experimental and DFT methods". supporting information. p. 103 - 119. Retrieved 2019/12/24.