Aztreonam lysine

Base Information

• Chemical Name: Aztreonam lysine
• CAS No.: 827611-49-4
• Molecular Formula: C13H17N5O8S2.C6H14N2O2
• Molecular Weight: 581.62000
• UNII: XNM7LT65NP
• NCI Thesaurus Code: C76021
• ChEMBL ID: CHEMBL3833340
• Mol file: 827611-49-4.mol

Synonyms:Aztreonam lysine;Aztreonam lysinate;Corus1020;Aztreonam l-lysine salt;CORUS-1020;Cayston;827611-49-4;Corus 1020;XNM7LT65NP;2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid;(2S)-2,6-diaminohexanoic acid;L-Lysine, mono(2-(((Z)-(1-(2-amino-4-thiazolyl)-2-(((2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino)-2-oxoethylidene)amino)oxy)-2-methylpropanoate);CHEMBL3833340;AZTREONAM LYSINE [MART.];AZTREONAM LYSINE [WHO-DD];AZTREONAM LYSINE [EMA EPAR];AZTREONAM L-LYSINE SALT [MI];AKOS040746610;L-LYSINE, 2-(((Z)-(1-(2-AMINO-4-THIAZOLYL)-2-(((2S,3S)-2-METHYL-4-OXO-1-SULFO-3-AZETIDINYL)AMINO)-2-OXOETHYLIDENE)AMINO)OXY)-2-METHYLPROPANOATE (1:1);L-LYSINE, MONO(2-(((Z)-(1-(2-AMINOTHIZOL-4-YL)-2-((2S,3S)-2-METHYL-4-OXO-1-SULFOAZETIDIN-3-YL)AMINO)-2-OXOETHYLIDENE)AMINO)OXY)-2-METHYLPROPANOATE

Chemical Property of Aztreonam lysine

Chemical Property:

• PSA: 327.54000
• LogP: 1.74620
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 16
• Rotatable Bond Count: 12
• Exact Mass: 581.15738256
• Heavy Atom Count: 38
• Complexity: 914

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1C(C(=O)N1S(=O)(=O)O)NC(=O)C(=NOC(C)(C)C(=O)O)C2=CSC(=N2)N.C(CCN)CC(C(=O)O)N
• Isomeric SMILES: C[C@H]1[C@@H](C(=O)N1S(=O)(=O)O)NC(=O)/C(=N\OC(C)(C)C(=O)O)/C2=CSC(=N2)N.C(CCN)C[C@@H](C(=O)O)N
• Recent ClinicalTrials: Value of Inhaled Treatment With Aztreonam Lysine in Bronchiectasis
• Recent EU Clinical Trials: A PROSPECTIVE, RANDOMIZED, OPEN-LABEL, COMPARATIVE STUDY TO ASSESS THE EFFICACY, SAFETY AND TOLERABILITY OF AZTREONAM-AVIBACTAM (ATM-AVI) AND BEST AVAILABLE THERAPY FOR THE TREATMENT OF SERIOUS INFECTIONS DUE TO MULTI-DRUG RESISTANT GRAM- NEGATIVE BACTERIA PRODUCING METALLO-Β-LACTAMASE (MBL)