fructose-phenylalanine

Base Information

• Chemical Name: fructose-phenylalanine
• CAS No.: 31105-03-0
• Molecular Formula: C15H21 N O7
• Molecular Weight: 327.3297
• Hs Code.: 2924299090
• Mol file: 31105-03-0.mol

Synonyms:D-Fructose,1-[(1-carboxy-2-phenylethyl)amino]-1-deoxy-, (S)-; Fructose, 1-[(L-a-carboxyphenethyl)amino]-1-deoxy-,D- (8CI); Fructose, 1-[(a-carboxyphenethyl)amino]-1-deoxy- (6CI,7CI);1-Deoxy-1-L-phenylalanino-D-fructose; 1-Deoxy-1-L-phenylalanyl-D-fructose;Fructose-phenylalanine; N-(1'-Carboxy-2'-phenylethyl)amino-1-deoxyfructose

Chemical Property of fructose-phenylalanine

Chemical Property:

• Vapor Pressure: 3.45E-19mmHg at 25°C
• Melting Point: >110°C (dec.)
• Boiling Point: 675.8°Cat760mmHg
• PKA: 2.01±0.10(Predicted)
• Flash Point: 362.5°C
• PSA: 147.32000
• Density: 1.423g/cm³
• LogP: -1.69310
• Storage Temp.: Refrigerator, Under Inert Atmosphere
• Solubility.: Methanol (Slightly), Water (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

Fructose-phenylalanine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: An Amadori compound having the potential to alter cellular adhesion, inhibit cancer metastasis and induce apoptosis.

Technology Process of fructose-phenylalanine

There total 3 articles about fructose-phenylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

D-glucose (50-99-7) + L-phenylalanine (63-91-2,25191-15-5,658-69-5,67675-33-6) → N-(1-deoxy-D-fructos-1-yl)-L-phenylalanine monohydrate (31105-03-0)

Guidance literature:

With sodium disulfite; In methanol; water; for 2h; Heating;

DOI:10.1016/0008-6215(83)88108-7

Reference yield:

D-Glucose (2280-44-6) + L-phenylalanine (63-91-2,25191-15-5,658-69-5,67675-33-6) → N-(1-deoxy-D-fructos-1-yl)-L-phenylalanine monohydrate (31105-03-0)

Guidance literature:

D-Glucose; L-phenylalanine; In methanol; N,N-dimethyl-formamide; for 3h; Heating;

With malonic acid; for 2h; Heating;

DOI:10.1021/jf000076e

Reference yield:

D-Fructose (57-48-7,18875-34-8) + L-phenylalanine (63-91-2,25191-15-5,658-69-5,67675-33-6) → N-(1-deoxy-D-fructos-1-yl)-L-phenylalanine monohydrate (31105-03-0) + N-D-glucose-2-yl-L-phenylalanine (112072-85-2)

Guidance literature:

With methanol;

upstream raw materials:

D-Fructose

L-phenylalanine

D-glucose

D-Glucose

Downstream raw materials:

N-(1-Desoxy-D-fructos-1-yl)-N-nitroso-L-phenylalanin

Refernces

• 1、 Abrams et al.. "-". . p. 4794. Retrieved 1955.
• 2、 Roeper, Harald,Roeper, Siyka,Heyns, Kurt,Meyer, Bernd. "N.M.R. SPECTROSCOPY OF N-(1-DEOXY-D-FRUCTOS-1-YL)-L-AMINO ACIDS ("FRUCTOSE-AMINO ACIDS")". . p. 183 - 196. Retrieved 2007/10/02.