Disulfide, bis(o-ethylphenyl)

Base Information

• Chemical Name: Disulfide, bis(o-ethylphenyl)
• CAS No.: 4500-66-7
• Molecular Formula: C16H18S2
• Molecular Weight: 274.451
• DSSTox Substance ID: DTXSID50196361
• Nikkaji Number: J867.909F
• Wikidata: Q83069427
• Mol file: 4500-66-7.mol

Synonyms:Disulfide, bis(o-ethylphenyl);4500-66-7;bis-(2-ethylphenyl)disulfide;Bis(2-ethylphenyl) persulfide;SCHEMBL775852;DTXSID50196361;RPTQMFYXBSBPNM-UHFFFAOYSA-N

Chemical Property of Disulfide, bis(o-ethylphenyl)

Chemical Property:

• Boiling Point: 363°Cat760mmHg
• Flash Point: 171.7°C
• Density: 1.12g/cm³
• XLogP3: 5.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 274.08499292
• Heavy Atom Count: 18
• Complexity: 205

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCC1=CC=CC=C1SSC2=CC=CC=C2CC

Technology Process of Disulfide, bis(o-ethylphenyl)

There total 7 articles about Disulfide, bis(o-ethylphenyl) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2-ethylthiophenol (4500-58-7) → 1,2-bis(2-ethylphenyl) disulfide (4500-66-7)

Guidance literature:

With sodium hydrogencarbonate; benzenesulfonyl chloride; In water; at 20 ℃; for 0.166667h;

DOI:10.1080/10426500802529051

Reference yield: 80.0%

1-ethyl-2-iodobenzene (18282-40-1) → 1,2-bis(2-ethylphenyl) disulfide (4500-66-7)

Guidance literature:

With carbon disulfide; cycl-isopropylidene malonate; triethylamine; copper(l) chloride; In N,N-dimethyl-formamide; at 100 ℃; for 4h; Reagent/catalyst; Temperature; Solvent; Inert atmosphere;

DOI:10.1016/j.tetlet.2015.12.085

Reference yield:

benzothiaferrole (12086-84-9) → bis(2-ethylphenyl) sulfide (27560-62-9) + ethylbenzene (100-41-4,27536-89-6) + 2-ethylthiophenol (4500-58-7) + 1,2-bis(2-ethylphenyl) disulfide (4500-66-7) + iron (7439-89-6)

Guidance literature:

With H₂; In hexane; react. of Fe-compound with H2 in hexane/anisol=125:1 in an autoclave cup (500 psig, 25°C), heating (175°C, 650 psig, 20 h); cooling and venting, filtn., GC-mass spectrometry for S-containing aromatics;

DOI:10.1021/om00095a024

upstream raw materials:

2-ethylthiophenol

o-Hydroxyethylbenzene

2-ethyl 0-phenyldimethylthiocarbamate

benzothiaferrole

Refernces

• 1、 Xiao, Huilong,Chen, Jiuxi,Liu, Miaochang,Wu, Huayue,Ding, Jinchang. "An approach to disulfide synthesis promoted by sulfonyl chloride in sodium bicarbonate aqueous media". experimental part. p. 2553 - 2559. Retrieved 2010/03/31.
• 2、 Ogilvy,Draganjac,Rauchfuss,Wilson. "ACTIVATION AND DESULFURIZATION OF THIOPHENE AND BENZOTHIOPHENE BY IRON CARBONYLS.". . p. 1171 - 1177. Retrieved 2008/10/08.