Urea, N-3-pyridinyl-

Base Information

• Chemical Name: Urea, N-3-pyridinyl-
• CAS No.: 13114-65-3
• Molecular Formula: C6H7 N3 O
• Molecular Weight: 137.141
• Mol file: 13114-65-3.mol

Synonyms:Urea,(3-pyridyl)- (7CI,8CI); Urea, 3-pyridinyl- (9CI); 1-(3-Pyridyl)urea;3-Pyridylcarbamide; 3-Ureidopyridine

Chemical Property of Urea, N-3-pyridinyl-

Chemical Property:

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Urea, N-3-pyridinyl-

There total 1 articles about Urea, N-3-pyridinyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.5%

nicotinyl hydroxamic acid (5657-61-4) → pyridin-3-ylamine (462-08-8) + 1-(pyridin-3-yl)urea (13114-65-3)

Guidance literature:

In formamide; at 130 - 150 ℃; for 20h;

Reference yield: 99.0%

1-(pyridin-3-yl)urea (13114-65-3) + methyl iodide (74-88-4) → (1-methylpyridinium-3-)-urea iodide (61392-06-1)

Guidance literature:

In methanol; for 6h; Heating;

DOI:10.1007/BF00764439

Reference yield: 85.0%

1-(pyridin-3-yl)urea (13114-65-3) + 1-benzyl-3,5-dichloro-6-methylpyrazin-2(1H)-one (173200-35-6) → 1-(4-benzyl-6-chloro-5-methyl-3-oxo-3,4-dihydropyrazin-2-yl)-3(pyridine-3-yl)urea

Guidance literature:

With palladium diacetate; caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,2-dimethoxyethane; at 80 - 100 ℃; for 0.416667h; Microwave irradiation;

DOI:10.1002/ejoc.201403405

upstream raw materials:

nicotinyl hydroxamic acid

Downstream raw materials:

(1-methylpyridinium-3-)-urea iodide

1-phenyl-3-pyridin-3-yl-urea

Refernces