N-CHLOROACETYL URETHANE

Base Information

• Chemical Name: N-CHLOROACETYL URETHANE
• CAS No.: 6092-47-3
• Molecular Formula: C5H8ClNO3
• Molecular Weight: 165.576
• Hs Code.: 29241900
• Mol file: 6092-47-3.mol

Synonyms:Ethyl (chloroacetyl)carbamate;N-2-Chloroacetylurethane;Ethyl N-(2-chloroacetyl)carbamate;

Chemical Property of N-CHLOROACETYL URETHANE

Chemical Property:

• Appearance/Colour: White or gray crystalline powder with corrosion smell
• Melting Point: 126-131 °C
• Refractive Index: 1.45
• PKA: 7.48±0.46(Predicted)
• PSA: 55.40000
• Density: 1.255 g/cm³
• LogP: 0.88880

Purity/Quality:

99%, ^*data from raw suppliers

Ethyl (chloroacetyl)carbamate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 21/22
• Safety Statements: 36/37

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-CHLOROACETYL URETHANE

There total 5 articles about N-CHLOROACETYL URETHANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

oxalyl dichloride (79-37-8) + ethanol (64-17-5) + Chloroacetamide (79-07-2) → ethyl (chloroacetyl)carbamate (6092-47-3)

Guidance literature:

oxalyl dichloride; Chloroacetamide; In 1,2-dichloro-ethane; at 0 - 90 ℃; for 4h;

ethanol; In 1,2-dichloro-ethane; at 0 ℃; for 0.0833333h;

DOI:10.3390/molecules25051138

Reference yield:

chloroacetyl chloride (79-04-9) + urethane (51-79-6) → ethyl (chloroacetyl)carbamate (6092-47-3)

Guidance literature:

DOI:10.1021/ja00858a016 DOI:10.1039/jr9600000983

Reference yield:

chloroacetic acid ethyl ester (105-39-5) → ethyl (chloroacetyl)carbamate (6092-47-3)

Guidance literature:

With diethyl ether;

upstream raw materials:

chloroacetyl chloride

urethane

ethanol

2-chloroacetylisocyanate

Downstream raw materials:

1-(4-chlorophenyl)imidazolidine-2,4-dione

1-(4-methoxyphenyl)hydantoin

1-(4-Bromophenyl)imidazolidine-2,4-dione

(4-Amino-2-benzylsulfanyl-thiazole-5-carbonyl)-carbamic acid ethyl ester

Refernces