Lithium acetate

Base Information

• Chemical Name: Lithium acetate
• CAS No.: 546-89-4
• Deprecated CAS: 2074561-07-0
• Molecular Formula: C2H3LiO2
• Molecular Weight: 65.9856
• Hs Code.: 29152990
• European Community (EC) Number: 208-914-3
• UNII: H4278O5FLV
• DSSTox Substance ID: DTXSID00883436
• Nikkaji Number: J423E
• Wikipedia: Lithium_acetate
• Wikidata: Q416969
• Mol file: 546-89-4.mol

Synonyms:lithium acetate;lithium acetate enolate anion

Chemical Property of Lithium acetate

Chemical Property:

• Appearance/Colour: solid
• Vapor Pressure: 13.9mmHg at 25°C
• Melting Point: 280-285 °C
• Boiling Point: 117.1 °C at 760 mmHg
• Flash Point: 40 °C
• PSA: 40.13000
• Density: 1.3[at 20℃]
• LogP: -1.24380
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility.: H2O: 5 M at 20 °C, clear, colorless
• Water Solubility.: 40.8 g/100 mL (20 ºC)
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 66.02930777
• Heavy Atom Count: 5
• Complexity: 34.6

Purity/Quality:

99% ^*data from raw suppliers

Lithium Acetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 23-24/25-39-26-22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Metals -> Organic Acids, Metal Salts
• Canonical SMILES: [Li+].CC(=O)[O-]
• Description: Lithium acetate (CH3COOLi) is a salt of lithium and acetic acid.
• Uses: Lithium acetate is used in the laboratory as buffer for gel electrophoresis of DNA and RNA. It has a lower electrical conductivity and can be run at higher speeds than can gels made from TAE buffer (5-30V/cm as compared to 5 - 10 V / cm). Lithium boric acid or sodium boric acid are usually preferable to lithium acetate or TAE when analyzing smaller fragments of DNA (less than 500 bp) due to the higher resolution of borate-based buffers in this size range as compared to acetate buffers. Lithium acetate is also used to permeabilize the cell wall of yeast for use in DNA transformation. It is believed that the beneficial effect of LiAc is caused by its chaotropic effect denaturing both DNA, RNA and proteins. Lithium acetate hydrate is used in the laboratory as buffer for gel electrophoresis of DNA and RNA. It is also used to permeabilize the cell wall of yeast for use in DNA transformation. It is a metal acetate for proteomics research. Lithium acetate (LiOAc) is a lithium source and a doping salt which can be used in the preparation of plasticized polymer electrolytes for lithium-ion batteries. It can be used as a monovalent cation, which improves the transformation efficiency of Saccharomyces cerevisiae.

Technology Process of Lithium acetate

There total 15 articles about Lithium acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.5%

→ lithium acetate (546-89-4)

Guidance literature:

Reference yield: 55.0%

lithium pentafluorobenzenesulfinate (36649-96-4) + mercury(II) diacetate (1600-27-7) → C6F5HgO(O)CCH3 (17314-19-1) + lithium acetate (546-89-4)

Guidance literature:

In water; in aq. suspension at 25°C, molar ratio of LiOS(O)C6F5 and Hg comp. = 1.0:2.1, immediately react.;

DOI:10.1016/S0022-1139(00)81712-1 DOI:10.1016/S0022-1139(00)82867-5

Reference yield:

4-nitrophenol acetate (830-03-5) → 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + lithium acetate (546-89-4)

Guidance literature:

With perchloric acid; water; lithium perchlorate; 2-amino-2-hydroxymethyl-1,3-propanediol; pH=7.3 - 8.9; Temperature; Activation energy; Kinetics; Mechanism;

upstream raw materials:

lithium tert-butyl hydroperoxide

acetone

n-butyllithium

[bis(acetoxy)iodo]benzene

Downstream raw materials:

acrylic acid methyl ester

Acetic acid (3aS,7aS)-1-(toluene-4-sulfonyl)-2,3,3a,4,5,7a-hexahydro-1H-indol-5-yl ester

1β-acetoxy-4β-chloro-6α-(benzyloxy)-2-cycloheptene

Acetic acid (1R,2S,6S)-6-benzyloxy-2-chloro-cyclohept-3-enyl ester

Refernces

• 1、 Birdwhistell, R. K.,Griswold, E.. "". . p. 873 - 875. Retrieved 1955.
• 2、 -. "Lithium-based metal organic frameworks". Page/Page column 6. . Retrieved 2014/09/17.