Technology Process of (1beta,2beta,3alpha)-1,2-epoxycrinan-3-ol
There total 4 articles about (1beta,2beta,3alpha)-1,2-epoxycrinan-3-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C16H17NO4;
With
triphenylphosphine; benzoic acid; diethylazodicarboxylate;
In
tetrahydrofuran;
at 80 ℃;
for 5h;
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
for 0.5h;
DOI:10.1039/c7sc02112g
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: C40H43ClIrN2P; potassium tert-butylate; hydrogen / ethanol / 0.5 h / 760.05 Torr
2.1: trifluoroacetic acid; dihydrogen peroxide; trichloroacetonitrile / dichloromethane; water / 48 h
3.1: triphenylphosphine; diethylazodicarboxylate; benzoic acid / tetrahydrofuran / 5 h / 80 °C
3.2: 0.5 h
With
C40H43ClIrN2P; potassium tert-butylate; hydrogen; dihydrogen peroxide; trichloroacetonitrile; triphenylphosphine; benzoic acid; trifluoroacetic acid; diethylazodicarboxylate;
In
tetrahydrofuran; ethanol; dichloromethane; water;
DOI:10.1039/c7sc02112g
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydroxide; water / methanol; tetrahydrofuran
2.1: trifluoroacetic acid; dihydrogen peroxide; trichloroacetonitrile / dichloromethane; water / 48 h
3.1: triphenylphosphine; diethylazodicarboxylate; benzoic acid / tetrahydrofuran / 5 h / 80 °C
3.2: 0.5 h
With
water; dihydrogen peroxide; trichloroacetonitrile; triphenylphosphine; benzoic acid; trifluoroacetic acid; sodium hydroxide; diethylazodicarboxylate;
In
tetrahydrofuran; methanol; dichloromethane; water;
DOI:10.1039/c7sc02112g
