Neuropeptide Y

Base Information

• Chemical Name: Neuropeptide Y
• CAS No.: 82785-45-3
• Deprecated CAS: 94717-03-0
• Molecular Formula: C190H287N55O57
• Molecular Weight: 4253.70
• UNII: BY7U39XXK0
• ChEMBL ID: CHEMBL267633
• DSSTox Substance ID: DTXSID4037164
• Pharos Ligand ID: 9TH8DQQ975L1
• Mol file: 82785-45-3.mol

Synonyms:Neuropeptide Tyrosine;Neuropeptide Y;Neuropeptide Y Like Immunoreactive Peptide;Neuropeptide Y-Like Immunoreactive Peptide;Tyrosine, Neuropeptide

Chemical Property of Neuropeptide Y

Chemical Property:

• PSA: 1832.36000
• LogP: 2.99310
• Storage Temp.: −20°C
• XLogP3: -15.5
• Hydrogen Bond Donor Count: 63
• Hydrogen Bond Acceptor Count: 64
• Rotatable Bond Count: 135
• Exact Mass: 4253.1316974
• Heavy Atom Count: 302
• Complexity: 10600

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCC(C)C(C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(C(C)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)N)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CC3=CN=CN3)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C6CCCN6C(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C7CCCN7C(=O)C(CC(=O)N)NC(=O)C(CC(=O)O)NC(=O)C8CCCN8C(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C9CCCN9C(=O)C(CC1=CC=C(C=C1)O)N
• Isomeric SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CC3=CN=CN3)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CC5=CC=C(C=C5)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H]6CCCN6C(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@@H]7CCCN7C(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H]8CCCN8C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]9CCCN9C(=O)[C@H](CC1=CC=C(C=C1)O)N
• Recent ClinicalTrials: Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)
• Recent EU Clinical Trials: A randomized , double-blind, placebo-controlled study of antidepressant effects of the endogen compound neuropeptide y (NPY) in patients suffering from major depressive disorder
• Biological functions: In the CNS, NPY induces food intake and decreases energy expenditure. NPY induces potent vasoconstriction. It also acts as a chemical mediator that controls the light-dark cycle entrainment of circadian rhythms. NPY modulates memory processes, depressive state, anxiety, stress, and seizure, and in the sympathetic nerve it stimulates catecholamine secretion.
• Description: Neuropeptide Y is a neuropeptide released by neurons in the CNS and sympathetic nerve system to induce several actions in the brain. In 1982, the isolation and identification of NPY from the porcine brain were reported.