6-Bromo-1,2,3,4-tetrahydronaphthalene

Base Information

• Chemical Name: 6-Bromo-1,2,3,4-tetrahydronaphthalene
• CAS No.: 6134-56-1
• Molecular Formula: C10H11 Br
• Molecular Weight: 211.101
• Hs Code.: 2903999090
• European Community (EC) Number: 820-420-5
• NSC Number: 174090
• DSSTox Substance ID: DTXSID50306100
• Nikkaji Number: J2.982.083J
• Wikidata: Q82053019
• Mol file: 6134-56-1.mol

Synonyms:6-bromo-1,2,3,4-tetrahydronaphthalene;6134-56-1;2-bromotetralin;6-bromotetralin;MFCD09842497;Naphthalene, 6-bromo-1,2,3,4-tetrahydro-;NSC174090;SCHEMBL749569;DTXSID50306100;AKOS000202634;NSC 174090;NSC-174090;6-bromo-1,2,3,4 tetrahydronaphthalene;2-Bromo-5,6,7,8-tetrahydronaphthalene;SY111062;CS-0130337;FT-0696617;EN300-64502;N10556;A868733;Z299596180

Chemical Property of 6-Bromo-1,2,3,4-tetrahydronaphthalene

Chemical Property:

• Vapor Pressure: 0.0193mmHg at 25°C
• Boiling Point: 260.9°C at 760 mmHg
• Flash Point: 113°C
• PSA: 0.00000
• Density: 1.384g/cm³
• LogP: 3.32790
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 210.00441
• Heavy Atom Count: 11
• Complexity: 133

Purity/Quality:

98% ^*data from raw suppliers

6-Bromo-1,2,3,4-tetrahydronaphthalene 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC2=C(C1)C=CC(=C2)Br

Technology Process of 6-Bromo-1,2,3,4-tetrahydronaphthalene

There total 11 articles about 6-Bromo-1,2,3,4-tetrahydronaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

7-bromo-3,4-dihydro-2H-naphthalen-1-one (32281-97-3) → 6-bromo-1,2,3,4-tetrahydronaphthalene (6134-56-1)

Guidance literature:

With triethylsilane; In trifluoroacetic acid; at 20 ℃;

DOI:10.1021/acs.joc.9b01844

Reference yield: 93.0%

tetralin (119-64-2) → 6-bromo-1,2,3,4-tetrahydronaphthalene (6134-56-1)

Guidance literature:

With benzyltrimethylazanium tribroman-2-uide; zinc(II) chloride; In acetic acid; for 1h; Ambient temperature;

DOI:10.1246/bcsj.62.439

Reference yield: 79.0%

4-oxo-4-(4-bromophenyl)butanoic acid (6340-79-0) → 6-bromo-1,2,3,4-tetrahydronaphthalene (6134-56-1)

Guidance literature:

With Dimethylphenylsilane; iodine; indium(III) acetate; In chloroform; at 60 ℃; for 5h; Inert atmosphere; Sealed tube;

DOI:10.1246/cl.150686

upstream raw materials:

6-amino-1,2,3,4-tetrahydronaphthalene

tetralin

trimethylbenzylammonium bromide

7-bromo-3,4-dihydro-2H-naphthalen-1-one

Downstream raw materials:

4,4,5,5-tetramethyl-2-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,2-dioxaborolane

(5,6,7,8-tetrahydronaphthalen-2-yl)boronic acid

4-[5,6,7,8-tetrahydro-naphthalen-2-yl]phenol

6-cyano-1,2,3,4-tetrahydronaphthalene

Refernces

• 1、 Nishii, Yuji,Ikeda, Mitsuhiro,Hayashi, Yoshihiro,Kawauchi, Susumu,Miura, Masahiro. "Triptycenyl Sulfide: A Practical and Active Catalyst for Electrophilic Aromatic Halogenation Using N-Halosuccinimides". supporting information. p. 1621 - 1629. Retrieved 2020/02/04.
• 2、 Shen, Jiaxuan,Li, Nannan,Yu, Yanjiang,Ma, Chunhua. "Visible-light-induced oxidation/[3 + 2] cycloaddition/oxidative aromatization to construct benzo[ a]carbazoles from 1,2,3,4-tetrahydronaphthalene and arylhydrazine hydrochlorides". supporting information. p. 7179 - 7183. Retrieved 2019/09/30.