gemeprost

Base Information

• Chemical Name: gemeprost
• CAS No.: 64318-79-2
• Molecular Formula: C23H38 O5
• Molecular Weight: 394.552
• Mol file: 64318-79-2.mol

Synonyms:16,16-Dimethyl-trans-D2-PGE methyl ester;16,16-Dimethyl-trans-D2-PGE1 methyl ester; 16,16-Dimethyl-trans-D2-prostaglandin E1 methyl ester; Carprost; Cergem;Cervagem; Cervageme; Gemeprost; Methyl 16,16-dimethyl-trans-D2-PGE1; ONO 802; Preglandin; SC37681; trans-2,3-Didehydro-16,16-dimethyl PGE1 methyl ester

Chemical Property of gemeprost

Chemical Property:

• Vapor Pressure: 1.47E-12mmHg at 25°C
• Refractive Index: 1.5800 (estimate)
• Boiling Point: 510.5oC at 760 mmHg
• PKA: 13.84±0.60(Predicted)
• Flash Point: 163.9oC
• PSA: 83.83000
• Density: 1.08g/cm3
• LogP: 3.97560

Purity/Quality:

98%,99%, ^*data from raw suppliers

Gemeprost ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Gemeprost, a metabolically stabilized analog of PGE1, has been demonstrated to reliably induce termination of early pregnancy when administered as a vaginal suppository. Its effect is presumably due to both uterine contraction and rapid decline of steroid hormone levels. Minimal side effects have been reported.
• Uses: Gemeprost is an analogue of Prostaglandin (P838600). Gemeprosts, similarly to Nitric Oxide donors, induce uterine cervical dilation and are used before surgical termination of pregnancy.
• Therapeutic Function: Prostaglandin, Cervical softener

Technology Process of gemeprost

There total 2 articles about gemeprost which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ gemeprost (64318-79-2)

Guidance literature:

Reference yield:

→ (E)-7-[(1R,3R)-3-Hydroxy-2-((E)-(R)-3-hydroxy-4,4-dimethyl-oct-1-enyl)-5-oxo-cyclopentyl]-hept-2-enoic acid methyl ester (64318-79-2,68372-87-2,68372-89-4,68399-10-0,85505-25-5,85505-26-6)

Guidance literature:

entspr. Bis-THP-Ether;

Refernces