2-BROMO-1,3,2-BENZODIOXAPHOSPHOLE

Base Information

• Chemical Name: 2-BROMO-1,3,2-BENZODIOXAPHOSPHOLE
• CAS No.: 3583-02-6
• Molecular Formula: C₆H₄BrO₂P
• Molecular Weight: 218.974
• Mol file: 3583-02-6.mol

Synonyms:Phosphorobromidousacid, cyclic o-phenylene ester (8CI);O-Phenylene phosphorobromidite (6CI,7CI);Pyrocatechol, cyclic phosphorobromidite;1,2-Phenylene phosphorobromidite((C6H4O2)BrP);NSC 310108;O-Phenylene phosphorobromidite ((C6H4O2)BrP);2-Bromo-1,3,2-benzodioxaphosphole;

Chemical Property of 2-BROMO-1,3,2-BENZODIOXAPHOSPHOLE

Chemical Property:

• Vapor Pressure: 0.0591mmHg at 25°C
• Boiling Point: 240.3 °C at 760 mmHg
• Flash Point: 99.2 °C
• PSA: 26.28000
• LogP: 3.73260

Purity/Quality:

99% ^*data from raw suppliers

2-BROMO-1,3,2-BENZODIOXAPHOSPHOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-BROMO-1,3,2-BENZODIOXAPHOSPHOLE

There total 6 articles about 2-BROMO-1,3,2-BENZODIOXAPHOSPHOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) → 2-bromo-1,3,2-benzodioxaphosphole (3583-02-6)

Guidance literature:

With water; phosphorus tribromide; 1.) 1 h; 2.) 100 deg C, 15 h;

DOI:10.1055/s-1993-25986

Reference yield:

2-hydroxy-1,3,2-benzodioxaphosphole (1195-15-9) → 2-bromo-1,3,2-benzodioxaphosphole (3583-02-6)

Guidance literature:

With Acetyl bromide; at 80 - 90 ℃; for 5h; Yield given;

Reference yield:

2,2,2-tribromo-1,3,2-benzodioxaphosphole (3712-44-5) + 2-(2,2,3,3-tetrafluoropropoxy)-4,5-benzo-1,3,2-dioxaphospholane (88399-68-2) → 2-bromo-1,3,2-benzodioxaphosphole (3583-02-6) + 2-(2,2,3,3-tetrafluoropropoxy)-2,2'-spirobi<1,3,2λ5-benzodioxaphosphole> (129993-38-0)

Guidance literature:

In dichloromethane; at 10 ℃; for 48h;

upstream raw materials:

benzene-1,2-diol

2,2,2-tribromo-1,3,2-benzodioxaphosphole

2-(2,2,3,3-tetrafluoropropoxy)-4,5-benzo-1,3,2-dioxaphospholane

2-hydroxy-1,3,2-benzodioxaphosphole

Downstream raw materials:

2-bromo-4-(4-bromophenyl)-2H-benzo[e][1,2]oxaphosphorin-3-ene 2-oxide

2-bromo-4-(4-bromophenyl)-2H-(4-bromobenzo)[e][1,2]oxaphosphorin-3-ene 2-oxide

phosphoric acid 2-hydroxyphenyl phosphate

2-hydroxyphenyl-2,2,3,3-tetrafluoropropylphosphoric acid

Refernces

• 1、 Ould, Darren M. C.,Tran, Thao T. P.,Rawson, Jeremy M.,Melen, Rebecca L.. "Structure-property-reactivity studies on dithiaphospholes". . p. 16922 - 16935. Retrieved 2019/11/26.
• 2、 Von Roman,Ruhdorfer,Knorr. "Alkenyl bromides by brominative deoxygenation of ketones in one or two steps". . p. 985 - 992. Retrieved 2007/10/02.