3,6-DIHYDRO-2H-PYRAN-4-BORONIC ACID

Base Information

• Chemical Name: 3,6-DIHYDRO-2H-PYRAN-4-BORONIC ACID
• CAS No.: 1002127-60-7
• Molecular Formula: C5H9BO3
• Molecular Weight: 127.936
• Hs Code.: 2932990090
• Mol file: 1002127-60-7.mol

Synonyms:(3,6-Dihydro-2H-pyran-4-yl)boronic acid

Chemical Property of 3,6-DIHYDRO-2H-PYRAN-4-BORONIC ACID

Chemical Property:

• PSA: 49.69000
• Density: 1.16
• LogP: -0.65490
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C

Purity/Quality:

98% ^*data from raw suppliers

3,6-Dihydro-2H-pyran-4-boronicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,6-DIHYDRO-2H-PYRAN-4-BORONIC ACID

There total 1 articles about 3,6-DIHYDRO-2H-PYRAN-4-BORONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyran (287944-16-5) → (3,6-dihydro-2H-pyran-4-yl)boronic acid (1002127-60-7)

Guidance literature:

With sodium periodate; ammonium acetate; In water; acetone; for 48h;

DOI:10.1002/anie.201202704

Reference yield: 76.0%

(3,6-dihydro-2H-pyran-4-yl)boronic acid (1002127-60-7) + 1-(5-bromo-7-((3,5-dimethoxyphenyl)amino)benzofuran-2-yl)ethan-1-one → 1-(5-(3,6-dihydro-2H-pyran-4-yl)-7-((3,5-dimethoxyphenyl)amino)benzofuran 2-yl)ethan-1-one

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate; In water; N,N-dimethyl-formamide; at 100 ℃; for 8h; Schlenk technique; Inert atmosphere;

DOI:10.1016/j.bmc.2020.115822

Reference yield: 72.0%

(3,6-dihydro-2H-pyran-4-yl)boronic acid (1002127-60-7) + α-phenylacrylanilide (64859-23-0) → 3-(3,6-dihydro-2H-pyran-4-yl)-N,2-diphenylpropanamide

Guidance literature:

With (μ2-Br)2Mn2(CO)8; ethanol; potassium carbonate; In diethyl ether; at 120 ℃; for 92h; chemoselective reaction; Schlenk technique;

DOI:10.1002/anie.201916305

upstream raw materials:

4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyran

Refernces