(3,3,3-TRIFLUOROPROPYL)BENZENE

Base Information

• Chemical Name: (3,3,3-TRIFLUOROPROPYL)BENZENE
• CAS No.: 1579-80-2
• Molecular Formula: C9H9F3
• Molecular Weight: 174.166
• Hs Code.: 2903999090
• Mol file: 1579-80-2.mol

Synonyms:(3,3,3-Trifluoropropyl)benzene;

Chemical Property of (3,3,3-TRIFLUOROPROPYL)BENZENE

Chemical Property:

• Refractive Index: 1.437
• Boiling Point: 151.5 °C at 760 mmHg
• Flash Point: 38.1 °C
• PSA: 0.00000
• Density: 1.122 g/cm³
• LogP: 3.18150

Purity/Quality:

99% ^*data from raw suppliers

(3,3,3-Trifluoropropyl)benzene 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3,3,3-TRIFLUOROPROPYL)BENZENE

There total 24 articles about (3,3,3-TRIFLUOROPROPYL)BENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + Bromotrifluoromethane (75-63-8) → (3,3,3-trifluoropropyl)benzene (1579-80-2)

Guidance literature:

With benzoic acid; zinc; In benzonitrile; at 20 ℃; Solvent; Reagent/catalyst;

Reference yield: 79.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + iodotrifluoromethane (2314-97-8,263005-66-9) → (3,3,3-trifluoropropyl)benzene (1579-80-2)

Guidance literature:

With 4-sulfanylphenol; In ethanol; 1,2-dichloro-ethane; at 23 ℃; for 18h; Schlenk technique; Microwave irradiation;

DOI:10.1002/anie.201608297

Reference yield: 70.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 4-dimethylamino-1-(trifluoromethyl)-sulfonylpyridin-1-ium trifluoromethanesulfonate → (3,3,3-trifluoropropyl)benzene (1579-80-2)

Guidance literature:

With fac-tris(2-phenylpyridinato-N,C₂')iridium(III); diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; phenylsilane; In 2,2,2-trifluoroethanol; acetonitrile; at 20 ℃; Schlenk technique; Irradiation; Inert atmosphere;

DOI:10.1021/acs.orglett.1c03630

upstream raw materials:

pentafluoroethyl phenyl ketone

3-Chloro-1,1,1-trifluoro-3-phenylpropane

2,2-dichloro-3,3,3-trifluoro-1-phenylpropyl methanesulfonate

1,1,1-trifluoropropylene

Downstream raw materials:

1,3-diphenylpropane

Refernces

• 1、 Louvel, Dan,Souibgui, Amel,Taponard, Alexis,Rouillon, Jean,ben Mosbah, Mongi,Moussaoui, Younes,Pilet, Guillaume,Khrouz, Lhoussain,Monnereau, Cyrille,Vantourout, Julien C.,Tlili, Anis. "Tailoring the Reactivity of the Langlois Reagent and Styrenes with Cyanoarenes Organophotocatalysts under Visible-Light". supporting information. p. 139 - 148. Retrieved 2021/10/25.
• 2、 -. "Method for preparing fluoroalkane substituted compound by reducing halogenated fluoroalkane and olefin through metal elementary substance". Paragraph 0029-0048. . Retrieved 2021/07/17.