1,3-dibromo-2-methyl-propane

Base Information

• Chemical Name: 1,3-dibromo-2-methyl-propane
• CAS No.: 28148-04-1
• Molecular Formula: C4H8Br2
• Molecular Weight: 215.916
• Hs Code.: 2903399090
• Mol file: 28148-04-1.mol

Synonyms:1,3-Dibromo-2-methylpropane;2-Methyl-1,3-dibromopropane;1,3-dibromo-2-methylpropane;Propane, 1,3-dibromo-2-methyl-;

Chemical Property of 1,3-dibromo-2-methyl-propane

Chemical Property:

• Vapor Pressure: 1.4mmHg at 25°C
• Melting Point: -25.98°C (estimate)
• Refractive Index: 1.505
• Boiling Point: 177.5 °C at 760 mmHg
• Flash Point: 48.8 °C
• PSA: 0.00000
• Density: 1.779 g/cm³
• LogP: 2.41230
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

1,3-Dibromo-2-methylpropane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-dibromo-2-methyl-propane

There total 5 articles about 1,3-dibromo-2-methyl-propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

1-bromo-butane (109-65-9) + 1-bromo-3-chloro-2-methyl propane (6974-77-2) → n-Butyl chloride (109-69-3) + 1,3-dibromo-2-methylpropane (28148-04-1)

Guidance literature:

With tetrabutylammomium bromide; at 105 - 110 ℃; Inert atmosphere; Schlenk technique;

DOI:10.1021/jo5025392

Reference yield: 71.0%

2-methyl-1.3-propanediol (2163-42-0) → 1,3-dibromo-2-methylpropane (28148-04-1)

Guidance literature:

With N-Bromosuccinimide; triphenylphosphine; In dichloromethane; at 0 - 20 ℃; for 0.5h;

DOI:10.1016/j.tet.2012.06.059

Reference yield:

2-methyl-3-bromo-1-propene (1458-98-6) → 1,3-dibromo-2-methylpropane (28148-04-1)

Guidance literature:

With air; dann mit Bromwasserstoff;

DOI:10.1021/ja01145a124

upstream raw materials:

2-methyl-3-bromo-1-propene

1,2-dibromo-2-methyl-propane

2-methyl-1.3-propanediol

1-bromo-butane

Downstream raw materials:

1,2-dibromo-2-methyl-propane

3-methyl-1-phenyl-cyclobutanecarbonitrile

isobutene

1,3-Bis(dimethylaminomethyl)-2-methylpropane

Refernces

• 1、 Byun, Woong Sub,Cha, Sangwon,Cui, Jinsheng,Hwang, Sunghoon,Kal, Youngju,Kim, Eunji,Lee, Sang Kook,Moon, Kyuho,Oh, Dong-Chan,Oh, Ki-Bong,Park, Jun Young,Park, So Hyun,Riandi, Evan Setiawan,Shin, Daniel,Shin, Jongheon,Sun, Jeongyoon,Yoon, Yeo Joon. "Structures and Biosynthetic Pathway of Pulvomycins B-D: 22-Membered Macrolides from an Estuarine Streptomyces sp.". . . Retrieved 2020.
• 2、 Mekala, Shekar,Hahn, Roger C.. "Process intensification-assisted conversion of α,ω-alkanediols to dibromides". supporting information. p. 630 - 632. Retrieved 2015/03/03.