N-Methacryloylglycine

Base Information

• Chemical Name: N-Methacryloylglycine
• CAS No.: 23578-45-2
• Molecular Formula: C6H9NO3
• Molecular Weight: 143.142
• Hs Code.: 2924199090
• Mol file: 23578-45-2.mol

Synonyms:Glycine,N-(2-methyl-1-oxo-2-propenyl)- (9CI);Glycine, N-methacryloyl- (6CI,8CI);Methacryloylaminoacetic acid;Methacryloylglycine;N-(Methylacryloyl)glycine;

Chemical Property of N-Methacryloylglycine

Chemical Property:

• Appearance/Colour: white crystal
• Vapor Pressure: 3.28E-07mmHg at 25°C
• Melting Point: 104 °C
• Refractive Index: 1.474
• Boiling Point: 391.2 °C at 760 mmHg
• PKA: 3.56±0.10(Predicted)
• Flash Point: 190.4 °C
• PSA: 66.40000
• Density: 1.163 g/cm³
• LogP: 0.15420
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

2-Methacrylamidoaceticacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N-Methacrylglycine is used in preparation method of fluorescence-adjustable europium-containing coordination polymer hydrogel film.

Technology Process of N-Methacryloylglycine

There total 4 articles about N-Methacryloylglycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

methacryloyl anhydride (760-93-0) + glycine (56-40-6,18875-39-3,25718-94-9) → N-methacryloylglycine (23578-45-2)

Guidance literature:

In water; acetonitrile; at 40 ℃; for 10h;

Reference yield: 60.8%

glycine (56-40-6,18875-39-3,25718-94-9) + Methacryloyl chloride (920-46-7,26937-45-1) → N-methacryloylglycine (23578-45-2)

Guidance literature:

With sodium hydroxide; In water;

DOI:10.1246/bcsj.58.1182

Reference yield:

poly(methacrylic acid) (79-41-4,25087-26-7,50867-57-7) + glycine (56-40-6,18875-39-3,25718-94-9) → N-methacryloylglycine (23578-45-2)

Guidance literature:

Multistep reaction; (i) SOCl₂, Et₂O, (ii) /BRN= 635782/, aq. NaOH;

DOI:10.1002/bms.1200061007

upstream raw materials:

glycine

Methacryloyl chloride

poly(methacrylic acid)

methacryloyl anhydride

Downstream raw materials:

N-(methacrylamidoacetyl) benzylamine

5-(N-methacryloylaminoacetoxy)-3,3-di(4-methoxyphenyl)-3H-naphtho[2,1-b]pyran

Refernces

• 1、 Sibrian-Vazquez, Martha,Spivak, David A.. "Improving the Strategy and Performance of Molecularly Imprinted Polymers Using Cross-Linking Functional Monomers". . p. 9604 - 9611. Retrieved 2003.
• 2、 -. "An organic silicon compound containing polymerized amide, due to their tropicalis tool and silicon-containing polymer". Paragraph 0078; 0081. . Retrieved 2016/10/10.
• 3、 Grachev,Bakova,Makhonina,Yurieva,Aldoshin,Gorelik,Barachevskii. "Synthesis and study of photochromic properties of copolymers based on functionalized chromenes". experimental part. p. 1469 - 1475. Retrieved 2012/07/13.