ASN-ASP-ASP-CYS-GLU-LEU-CYS-VAL-ASN-VAL-ALA-CYS-THR-GLY-CYS-LEU

Base Information

• Chemical Name: ASN-ASP-ASP-CYS-GLU-LEU-CYS-VAL-ASN-VAL-ALA-CYS-THR-GLY-CYS-LEU
• CAS No.: 154525-25-4
• Molecular Formula: C64H102 N18 O26 S4
• Molecular Weight: 1667.86
• Mol file: 154525-25-4.mol

Synonyms:27,28,40,41-Tetrathia-2,5,8,11,14,17,20,23,31,34,37-undecaazabicyclo[14.13.13]dotetracontane,cyclic peptide deriv.; 1: PN: WO02078683 SEQID: 1 claimed protein; Humanuroguanylin; L-Leucine, L-asparaginyl-L-a-aspartyl-L-a-aspartyl-L-cysteinyl-L-a-glutamyl-L-leucyl-L-cysteinyl-L-valyl-L-asparaginyl-L-valyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-,cyclic (4®12),(7®15)-bis(disulfide)

Chemical Property of ASN-ASP-ASP-CYS-GLU-LEU-CYS-VAL-ASN-VAL-ALA-CYS-THR-GLY-CYS-LEU

Chemical Property:

• Boiling Point: 2112.5±65.0 °C(Predicted)
• PKA: 3.61±0.21(Predicted)
• PSA: 819.33000
• Density: 1.48±0.1 g/cm3(Predicted)
• LogP: -1.25710
• Storage Temp.: −20°C

Purity/Quality:

99% ^*data from raw suppliers

Uroguanylin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Clinical Use: Two UGN/GN agonists, linaclotide and plecanatide, have recently been approved in the United States, European Union, Japan, and other countries for treatment of irritable bowel syndrome and chronic constipation. They have also been approved in the United States for treatment of chronic idiopathic constipation and irritable bowel syndrome with constipation, respectively.