2-amino-5-chloro-N-methylbenzohydrazide

Base Information

• Chemical Name: 2-amino-5-chloro-N-methylbenzohydrazide
• CAS No.: 59169-70-9
• Molecular Formula: C₈H₁₀ClN₃O
• Molecular Weight: 199.64
• DSSTox Substance ID: DTXSID90369299
• Wikidata: Q82156350
• Mol file: 59169-70-9.mol

Synonyms:2-amino-5-chloro-N-methylbenzohydrazide;59169-70-9;1-(2-Amino-5-chlorobenzoyl)-1-methylhydrazine;1-(2-Amino-5-chlorobenzoyl)-1-methyl-hydrazine;DTXSID90369299;XWQSAOBUBKQAII-UHFFFAOYSA-N;AKOS015891552;2-azanyl-5-chloranyl-N-methyl-benzohydrazide;FT-0640588;1-(2-Amino-5-chlorobenzoyl)-1-methyl hydrazine;A832193;1-[4-(4-TRIFLUOROMETHOXY-PHENOXY)-PHENYL]-ETHANONE

Chemical Property of 2-amino-5-chloro-N-methylbenzohydrazide

Chemical Property:

• Appearance/Colour: Light brown crystalline powder and chunks
• Vapor Pressure: 3.97E-06mmHg at 25°C
• Melting Point: 78-81 °C
• Refractive Index: 1.64
• Boiling Point: 384.9 °C at 760 mmHg
• Flash Point: 186.6 °C
• PSA: 72.35000
• Density: 1.366 g/cm³
• LogP: 2.14940
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 199.0512396
• Heavy Atom Count: 13
• Complexity: 200

Purity/Quality:

98%Min ^*data from raw suppliers

1-(2-AMINO-5-CHLOROBENZOYL)-1-METHYLHYDRAZINE 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C(=O)C1=C(C=CC(=C1)Cl)N)N

Technology Process of 2-amino-5-chloro-N-methylbenzohydrazide

There total 2 articles about 2-amino-5-chloro-N-methylbenzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

5-Chloroisatoic anhydride (4743-17-3) + isatoic anhydride (118-48-9) → 1-(2'-amino-5'-chlorobenzoyl)-1-methylhydrazine (59169-70-9) + 2-amino-5-chloro-benzoic acid N'-methyl-hydrazide

Guidance literature:

In ethanol; for 4h;

Reference yield:

→ 1-(2'-amino-5'-chlorobenzoyl)-1-methylhydrazine (59169-70-9)

Guidance literature:

/BRN= 11335/, MeNHNH2;

Reference yield: 66.0%

1-(2'-amino-5'-chlorobenzoyl)-1-methylhydrazine (59169-70-9) + 3-Methyl-2,4-pentanedione (815-57-6) → 4--3-methyl-4-penten-2-one (81622-66-4)

Guidance literature:

for 5h;

DOI:10.1016/0040-4020(82)85022-9

upstream raw materials:

5-Chloroisatoic anhydride

isatoic anhydride

Downstream raw materials:

4--3-methyl-4-penten-2-one

Refernces