6'-N-methylsisomicin

Base Information

• Chemical Name: 6'-N-methylsisomicin
• CAS No.: 51909-61-6
• Molecular Formula: C₂₀H₃₉N₅O₇
• Molecular Weight: 461.559
• Mol file: 51909-61-6.mol

Synonyms:AntibioticG 52

Chemical Property of 6'-N-methylsisomicin

Chemical Property:

• Vapor Pressure: 7.53E-21mmHg at 25°C
• Refractive Index: 1.7600 (estimate)
• Boiling Point: 670.6°Cat760mmHg
• Flash Point: 359.3°C
• PSA: 199.73000
• Density: 1.34g/cm³
• LogP: -0.70810

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6'-N-methylsisomicin

There total 2 articles about 6'-N-methylsisomicin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C20H33N11O7 → G-52 (51909-61-6)

Guidance literature:

With water; trimethylphosphane; In tetrahydrofuran; methanol; for 1h; Inert atmosphere;

DOI:10.1021/ol802421d

Reference yield:

→ G-52 (51909-61-6)

Guidance literature:

Aus dem Aminoglycosid 66-4OC, Methylamin, H3PO4, NaBH4;

DOI:10.1021/jm00200a009

Refernces

• 1、 Davies,Mallams,Counelis,Loebenberg,Moss Jr.,Waitz. "Semisynthetic aminoglycoside antibacterials. 6. Synthesis of sisomicin, antibiotic G-52, and novel 6'-substituted analogues of sisomicin from aminoglycoside 66-40C". . p. 189 - 193. Retrieved 2007/10/05.