ASISCHEM N61996

Base Information

• Chemical Name: ASISCHEM N61996
• CAS No.: 794-65-0
• Molecular Formula: C13H8 N2 O6
• Molecular Weight: 288.216
• Hs Code.: 2913000090
• Mol file: 794-65-0.mol

Synonyms:Benzaldehyde, p-(2,4-dinitrophenoxy)- (6CI,7CI,8CI); NSC233873; p-(2,4-Dinitrophenoxy)benzaldehyde

Chemical Property of ASISCHEM N61996

Chemical Property:

• Vapor Pressure: 2.09E-07mmHg at 25°C
• Melting Point: 105 °C
• Boiling Point: 424.3°Cat760mmHg
• Flash Point: 189.1°C
• PSA: 117.94000
• Density: 1.475g/cm³
• LogP: 4.15420

Purity/Quality:

99% ^*data from raw suppliers

4-(2,4-Dinitrophenoxy)benzaldehyde 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ASISCHEM N61996

There total 3 articles about ASISCHEM N61996 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) + 1-chloro-2,4-dinitro-benzene (97-00-7) → 1-(4-formylphenoxy)-2,4-dinitrobenzene (794-65-0)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/j.bmc.2020.115990

Reference yield:

2,4-Dinitrofluorobenzene (70-34-8,65727-75-5) + 4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → 1-(4-formylphenoxy)-2,4-dinitrobenzene (794-65-0)

Guidance literature:

With sodium hydrogencarbonate; acetone;

Reference yield:

→ 1-(4-formylphenoxy)-2,4-dinitrobenzene (794-65-0)

Guidance literature:

(2,4-Dinitro-phenyl)-(4-methansulfonyl-phenyl)-ether, Kalium-(4-formyl-phenolat), DMF;

upstream raw materials:

2,4-Dinitrofluorobenzene

4-hydroxy-benzaldehyde

1-chloro-2,4-dinitro-benzene

Downstream raw materials:

4-(2,4-dinitro-phenoxy)-3-nitro-benzaldehyde

1-(2,4-dinitrophenyl)piperidine

1-azido-2,4-dinitrobenzene

2,4-Dinitrophenol

Refernces

• 1、 Makley, Leah N.,Johnson, Oleta T.,Ghanakota, Phani,Rauch, Jennifer N.,Osborn, Delaney,Wu, Taia S.,Cierpicki, Tomasz,Carlson, Heather A.,Gestwicki, Jason E.. "Chemical validation of a druggable site on Hsp27/HSPB1 using in silico solvent mapping and biophysical methods". . . Retrieved 2021/02/09.
• 2、 Seo, Hyeon-Ok,Kim, Min-Young,Han, So-Yeop,Um, Ik-Hwan. "Kinetic study on SNAr reactions of 1-(Y-substituted-phenoxy)-2,4-dinitrobenzenes with Azide ion: Effect of changing nucleophile from hydroxide to Azide ion on reaction mechanism and reactivity". . p. 1764 - 1768. Retrieved 2015/07/15.