Z-His-OH

Base Information Edit

Chemical Name:Z-His-OH
CAS No.:14997-58-1
Molecular Formula:C14H15N3O4
Molecular Weight:289.291
Hs Code.:29332900
European Community (EC) Number:239-084-0
DSSTox Substance ID:DTXSID501280353
Nikkaji Number:J26.598E
Mol file:14997-58-1.mol

Synonyms:14997-58-1;Z-His-OH;N-Cbz-L-histidine;L-Histidine, N-[(phenylmethoxy)carbonyl]-;CBZ-histidine;Nalpha-Cbz-L-histidine;Nalpha-Carbobenzoxy-L-histidine;Cbz-His-OH;(2S)-3-(1H-imidazol-5-yl)-2-(phenylmethoxycarbonylamino)propanoic acid;N-(alpha)-Carbobenzoxy-L-histidine;N-[(Benzyloxy)carbonyl]-L-histidine;MFCD00065960;(2S)-2-{[(benzyloxy)carbonyl]amino}-3-(1H-imidazol-4-yl)propanoic acid;(s)-2-(((benzyloxy)carbonyl)amino)-3-(1h-imidazol-5-yl)propanoic acid;N-Benzyloxycarbonyl-L-histidine;EINECS 239-084-0;Cbz-L-histidine;Cbz-His;N-alpha-benzyloxycarbonyl-L-histidine;Z-L-HISTIDINE;benzyloxycarbonyl-L-histidine;N-CBZ-L-HISTIDINE-OH;Z-His-OH, 99%;SCHEMBL254638;SCHEMBL9230979;((Benzyloxy)carbonyl)-L-histidine;DTXSID501280353;Nalpha -benzyloxycarbonyl-histidine;AMY31373;(S)-2-(BENZYLOXYCARBONYLAMINO)-3-(1H-IMIDAZOL-4-YL)PROPANOIC ACID;AKOS015909985;AKOS015924085;CS-W013996;FD21657;HY-W013280;Histidine, N-[(phenylmethoxy)carbonyl]-;N-[(Phenylmethoxy)carbonyl]-L-histidine;AC-17159;AS-49151;B0265;EN300-121289;A808989;W-108080

Suppliers and Price of Z-His-OH

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
N-alpha-Z-L-histidine
5g
$ 333.00

TRC
Nα-Cbz-L-histidine
5g
$ 150.00

TRC
Nα-Cbz-L-histidine
100g
$ 1780.00

TCI Chemical
Nalpha-Carbobenzoxy-L-histidine >99.0%(T)
1g
$ 51.00

TCI Chemical
Nalpha-Carbobenzoxy-L-histidine >99.0%(T)
25g
$ 527.00

TCI Chemical
Nalpha-Carbobenzoxy-L-histidine >99.0%(T)
5g
$ 145.00

Sigma-Aldrich
Z-His-OH 99%
5g
$ 162.00

Iris Biotech GmbH
Z-L-His-OH
25 g
$ 270.00

Iris Biotech GmbH
Z-L-His-OH
5 g
$ 87.75

Frontier Specialty Chemicals
Z-His-OH 98%
1g
$ 44.00

Total 72 raw suppliers

Chemical Property of Z-His-OH Edit

Chemical Property:

Appearance/Colour:White to off-white microcrystalline powder
Vapor Pressure:4.56E-16mmHg at 25°C
Melting Point:168 °C (dec.)(lit.)
Refractive Index:-23.5 ° (C=6, 6mol/L HCl)
Boiling Point:616.7 °C at 760 mmHg
PKA:3.35±0.10(Predicted)
Flash Point:326.8 °C
PSA：104.31000
Density:1.368 g/cm³
LogP:1.72270
Storage Temp.:−20°C
Water Solubility.:almost transparency
XLogP3:1.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:289.10625597
Heavy Atom Count:21
Complexity:358

Purity/Quality:

99% ^*data from raw suppliers

N-alpha-Z-L-histidine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 20/21/22-36/37/38
Safety Statements: 22-24/25-36-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC(=O)NC(CC2=CN=CN2)C(=O)O
Isomeric SMILES:C1=CC=C(C=C1)COC(=O)N[C@@H](CC2=CN=CN2)C(=O)O
Uses Nα-Cbz-L-histidine is an N-Cbz-protected form of L-Histidine (H456010). L-Histidine is an essential amino acid that plays an important role in mitochondrial glutamine transport and has potential of abolishing oxidative stress caused by brain edema.L-Histidine promotes zinc uptake in human erythrocyes and also has potential as an antioxidant therapy for acute mammary inflammation in cattle.

Technology Process of Z-His-OH

There total 24 articles about Z-His-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%