Wln: T B6566 B6/CO 4abbc R BX HO PN DU ght&&ttj FQ JO1 P1

Base Information

• Chemical Name: Wln: T B6566 B6/CO 4abbc R BX HO PN DU ght&&ttj FQ JO1 P1
• CAS No.: 7235-41-8
• Molecular Formula: C₁₈H₂₁NO₃
• Molecular Weight: 299.37
• NSC Number: 76434
• Mol file: 7235-41-8.mol

Synonyms:6-Isocodeine;NSC-76434;SCHEMBL15580917;NSC76434;Morphinan-6.beta.-ol,8-didehydro-4,5.alpha.-epoxy-3-methoxy-17-methyl-;WLN: T B6566 B6/CO 4ABBC R BX HO PN DU GHT&&TTJ FQ JO1 P1;Morphinan-6-ol,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5.alpha.,6.beta.)-

Chemical Property of Wln: T B6566 B6/CO 4abbc R BX HO PN DU ght&&ttj FQ JO1 P1

Chemical Property:

• Vapor Pressure: 2.58E-11mmHg at 25°C
• Boiling Point: 529.9°Cat760mmHg
• Flash Point: 274.3°C
• Density: 1.25g/cm³
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 299.15214353
• Heavy Atom Count: 22
• Complexity: 509

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(C=C4)O
• Isomeric SMILES: CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3C(C=C4)O

Technology Process of Wln: T B6566 B6/CO 4abbc R BX HO PN DU ght&&ttj FQ JO1 P1

There total 17 articles about Wln: T B6566 B6/CO 4abbc R BX HO PN DU ght&&ttj FQ JO1 P1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

C20H22BrNO5 → hydrocodone (76-57-3,509-64-8,7235-41-8,16206-70-5,27067-72-7,64520-25-8,70982-46-6)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 25 ℃; for 6h;

Reference yield:

→ hydrocodone (76-57-3,509-64-8,7235-41-8,16206-70-5,27067-72-7,64520-25-8,70982-46-6)

Guidance literature:

Codeinon durch Erhitzen mit Al-isopropylat in Isopropanol nach Meerwein-Ponndorf-Verley;

Reference yield:

6β-chloro-4,5α-epoxy-3-methoxy-17-methyl-morphin-7-ene (467-08-3) → isocodeine (76-57-3,509-64-8,7235-41-8,16206-70-5,27067-72-7,64520-25-8,70982-46-6) + pseudocodeine (466-96-6)

Guidance literature:

With acetic acid; for 2h; Title compound not separated from byproducts; Heating;

upstream raw materials:

6β-chloro-4,5α-epoxy-3-methoxy-17-methyl-morphin-7-ene

Downstream raw materials:

isocodeine benzyl dithiocarbonate

8β-chloro-4,5α-epoxy-3-methoxy-17-methyl-morphin-6-ene

(+/-)-morphine

codeine phosphate

Refernces

• 1、 -. "SYNTHESIS OF MORPHINE AND RELATED DERIVATIVES". Page/Page column 84-85. . Retrieved 2010/12/17.
• 2、 -. "Process for converting neopinone to codeinone". . . Retrieved 2008/06/13.