SODIUM 4-PYRIDINECARBOXYLATE TETRAHYDRATE

Base Information

• Chemical Name: SODIUM 4-PYRIDINECARBOXYLATE TETRAHYDRATE
• CAS No.: 16887-79-9
• Molecular Formula: C6H5 N O2 . Na
• Molecular Weight: 145.10
• Mol file: 16887-79-9.mol

Synonyms:4-Pyridinecarboxylicacid, sodium salt (9CI); Isonicotinic acid, sodium salt (8CI); Sodium4-picolinate; Sodium 4-pyridinecarboxylate; Sodium isonicotinate

Chemical Property of SODIUM 4-PYRIDINECARBOXYLATE TETRAHYDRATE

Chemical Property:

• Vapor Pressure: 5.56E-07mmHg at 25°C
• Boiling Point: 396 °C at 760 mmHg
• Flash Point: 193.3 °C
• PSA: 53.02000
• Density: g/cm³
• LogP: -0.55490
• Storage Temp.: Inert atmosphere,Room Temperature
• Water Solubility.: almost transparency

Purity/Quality:

98%,99%, ^*data from raw suppliers

Sodium4-Pyridinecarboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of SODIUM 4-PYRIDINECARBOXYLATE TETRAHYDRATE

There total 5 articles about SODIUM 4-PYRIDINECARBOXYLATE TETRAHYDRATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

pyridine-4-carboxylic acid (55-22-1) → sodium pyridine-4-carboxylate (16887-79-9)

Guidance literature:

With sodium hydroxide; In water; at 20 ℃; for 0.5h;

DOI:10.1039/d0nj00753f

Reference yield: 18.0%

4-(1-hydroxy-1-(4-pyridyl)methyl)-1-nitrobenzene (178809-75-1) → sodium pyridine-4-carboxylate (16887-79-9) + [4-(4-Hydroxy-phenylazo)-phenyl]-pyridin-4-yl-methanone + {4-[4-(Pyridine-4-carbonyl)-phenylazo]-phenyl}-pyridin-4-yl-methanone + {4-[4-(Pyridine-4-carbonyl)-phenyl-NNO-azoxy]-phenyl}-pyridin-4-yl-methanone

Guidance literature:

With sodium hydroxide; for 1h; Heating;

DOI:10.1002/jhet.5570330206

Reference yield:

4-pyridinecarbohydroxamic acid (4427-22-9) → sodium pyridine-4-carboxylate (16887-79-9)

Guidance literature:

With potassium hexacyanoferrate(III); In aq. phosphate buffer; at 20 ℃; for 322h; pH=7.4; Solvent; Time;

DOI:10.1039/d0nj00753f

upstream raw materials:

4-(1-hydroxy-1-(4-pyridyl)methyl)-1-nitrobenzene

4-Nitrobenzylpyridin

(4-nitrophenyl)(pyridin-4-yl)methanone

pyridine-4-carboxylic acid

Downstream raw materials:

bromure de pyridine-4 carbonyloxy-3 propyltriphenylphosphonium

N-(2-(tert-butylcarbamoyl)phenyl)isonicotinamide

[Rh₂(N,N'-di-p-tolylformamidinate)2(isonicotinate)2]

1,2-ethanediyl di-4-pyridine carboxylate

Refernces

• 1、 ?widerski, Grzegorz,Kalinowska, Monika,Wilczewska, Agnieszka Z.,Malejko, Julita,Lewandowski, W?odzimierz. "Lanthanide complexes with pyridinecarboxylic acids – Spectroscopic and thermal studies". . p. 97 - 109. Retrieved 2018.
• 2、 Carvalho, Edinilton Muniz,Rechignat, Lionel,Sousa, Eduardo Henrique Silva De,Lopes, Luiz Gonzaga De Fran?a,Chauvin, Remi,Bernardes-Génisson, Vania. "Mechanistic insights into the: In vitro metal-promoted oxidation of (di)azine hydroxamic acids: Evidence of HNO release and N, O -di(di)azinoyl hydroxylamine intermediate". supporting information. p. 11965 - 11973. Retrieved 2020/07/30.