2-Furanacrylamide

Base Information

• Chemical Name: 2-Furanacrylamide
• CAS No.: 623-16-5
• Molecular Formula: C7H7NO2
• Molecular Weight: 137.136
• NSC Number: 4674
• UNII: 3DR68K8F6Y
• Nikkaji Number: J95.517E,J2.460.192G
• Mol file: 623-16-5.mol

Synonyms:2-FURANACRYLAMIDE;3-(2-Furanyl)-2-propenamide;2-Propenamide, 3-(2-furanyl)-;25525-85-3;623-16-5;AI3-00508;3-Furan-2-yl-acrylamide;(E)-3-(furan-2-yl)prop-2-enamide;NSC-4674;(2e)-3-(2-furyl)acrylamide;2-Furanpropenamide;Furfuracrylic amide;2-Furfurylideneacetamide;NSC 4674;(E)-3-(furan-2-yl)acrylamide;NSC4674;3-(2-furyl)acrylamide;3DR68K8F6Y;HMS1659P03;STK010817;AKOS000492175;(2E)-3-(furan-2-yl)prop-2-enamide;AJ-087/25124012;F3145-1960

Chemical Property of 2-Furanacrylamide

Chemical Property:

• Vapor Pressure: 0.000193mmHg at 25°C
• Refractive Index: 1.581
• Boiling Point: 328.1 °C at 760 mmHg
• Flash Point: 152.2 °C
• Density: 1.202 g/cm³
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 137.047678466
• Heavy Atom Count: 10
• Complexity: 154

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=COC(=C1)C=CC(=O)N
• Isomeric SMILES: C1=COC(=C1)/C=C/C(=O)N

Technology Process of 2-Furanacrylamide

There total 2 articles about 2-Furanacrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

FAOH (623-31-4) → -3-(furan-2-yl)acrylamide (623-16-5)

Guidance literature:

With C₅₅H₄₅ClN₅P₂Ru⁽¹⁺⁾*Cl^(1-); In water; at 110 ℃; for 12h; Sealed tube;

DOI:10.1039/c6ra07515k

Reference yield:

furfural (98-01-1) + bromo-acetic acid amide (683-57-8) → -3-(furan-2-yl)acrylamide (623-16-5)

Guidance literature:

With 2-propenamide; triphenylphosphine; In propan-1-ol; at 90 ℃; Inert atmosphere;

DOI:10.1021/ja306407x

upstream raw materials:

furfural

bromo-acetic acid amide

FAOH

Refernces

• 1、 Wu, Xue-Song,Chen, Yan,Li, Man-Bo,Zhou, Meng-Guang,Tian, Shi-Kai. "Direct substitution of primary allylic amines with sulfinate salts". supporting information. p. 14694 - 14697. Retrieved 2012/11/07.