Heptafluoro-1-methoxypropane

Base Information

• Chemical Name: Heptafluoro-1-methoxypropane
• CAS No.: 375-03-1
• Deprecated CAS: 214051-29-3,1610350-01-0,1610350-01-0
• Molecular Formula: C4H3 F7 O
• Molecular Weight: 200.056
• Hs Code.: 2909199090
• European Community (EC) Number: 609-440-3
• DSSTox Substance ID: DTXSID7074909
• Nikkaji Number: J641.708F
• Wikidata: Q66084471
• Mol file: 375-03-1.mol

Synonyms:Heptafluoro-1-methoxypropane;375-03-1;1,1,1,2,2,3,3-Heptafluoro-3-methoxypropane;heptafluoropropyl methyl ether;Propane, 1,1,1,2,2,3,3-heptafluoro-3-methoxy-;HFE 347mcc;Novec HFE 7000;Perfluoropropyl methyl ether;R-E 347mcc1;HFE 301;HFE 347;HFE 7000;E 347;1,1,1,2,2,3,3-heptafluoro-3-methoxy-propane;Methyl heptafluoropropyl ether;C3F7OCH3;SCHEMBL34678;DTXSID7074909;AMY6889;HFE-7000;MFCD01320779;AKOS015852676;AS-48053;FT-0676399;H1773;F17601;A823708;QUINAZOLINE,4,6-DICHLORO-2-(CHLOROMETHYL)-

Chemical Property of Heptafluoro-1-methoxypropane

Chemical Property:

• Melting Point: -123
• Refractive Index: 1.3597 (estimate)
• Boiling Point: 34
• Flash Point: °C
• PSA: 9.23000
• Density: 1.437g/cm³
• LogP: 2.42320
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 2
• Exact Mass: 200.00721185
• Heavy Atom Count: 12
• Complexity: 159

Purity/Quality:

99%, ^*data from raw suppliers

Heptafluoro-1-methoxypropane 99.5% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Classes -> Halogenated Ethers
• Canonical SMILES: COC(C(C(F)(F)F)(F)F)(F)F
• Uses: Heptafluoro-1-methoxypropane is used in preparation method of Isolated Hydrofluoroether.

Technology Process of Heptafluoro-1-methoxypropane

There total 10 articles about Heptafluoro-1-methoxypropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

Ethyl pentafluoro-1-propenyl ether (666-92-2) → heptafluoropropyl methyl ether (375-03-1)

Guidance literature:

With perfluoropropylene; at 100 ℃; for 3.5h;

Reference yield: 83.7%

perfluoropropanoyl fluoride (422-61-7) + carbonic acid dimethyl ester (616-38-6) → heptafluoropropyl methyl ether (375-03-1)

Guidance literature:

perfluoropropanoyl fluoride; With potassium fluoride; at 20 ℃; for 24h; Autoclave;

carbonic acid dimethyl ester; With water; at 20 ℃; for 36h; Autoclave;

Reference yield: 55.0%

Ethyl pentafluoro-1-propenyl ether (666-92-2) → heptafluoropropyl methyl ether (375-03-1) + 1,1,1,2,2,3,3-heptafluoro-3-fluoromethoxypropane (184899-81-8)

Guidance literature:

With cobalt (III) fluoride; at -196 - 20 ℃; for 0.5h;

upstream raw materials:

2,3-bis(fluorosulfato)perfluoro-(2-methylpentane)

dimethyl sulfate

Ethyl pentafluoro-1-propenyl ether

ethanol

Downstream raw materials:

Carbonyl fluoride

perfluoropropanoyl fluoride

heptafluoropropionyl formate

N,N,N-trimethyl-1-phenylmethanaminium perfluoropropoxide

Refernces

• 1、 -. "Method for preparing fluorine-containing ether". Paragraph 0084-0085. . Retrieved 2019/07/29.
• 2、 Galimberti, Marco,Fontana, Giovanni,Resnati, Giuseppe,Navarrini, Walter. "New catalytic alkylation of in situ generated perfluoro-alkyloxy-anions and perfluoro-carbanions". . p. 1578 - 1586. Retrieved 2007/10/03.