Doxorubicin(6-maleimidocaproyl)hydrazone

Base Information Edit

Chemical Name:Doxorubicin(6-maleimidocaproyl)hydrazone
CAS No.:151038-96-9
Molecular Formula:C₃₇H₄₂N₄O₁₃
Molecular Weight:750.759
Hs Code.:
Wikipedia:Aldoxorubicin
NCI Thesaurus Code:C68921
Mol file:151038-96-9.mol

Synonyms:doxorubicin(6-maleimidocaproyl)hydrazone;MC-DOXHZN

Suppliers and Price of Doxorubicin(6-maleimidocaproyl)hydrazone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
DOXO-EMCH 98+%
10mg
$ 170.00

Crysdot
DOXO-EMCH 98+%
25mg
$ 325.00

ApexBio Technology
DOXO-EMCH
10mg
$ 255.00

ApexBio Technology
DOXO-EMCH
5mg
$ 188.00

ApexBio Technology
DOXO-EMCH
2mg
$ 113.00

ApexBio Technology
DOXO-EMCH
50mg
$ 960.00

American Custom Chemicals Corporation
INNO-206 95.00%
5MG
$ 922.30

Total 22 raw suppliers

Chemical Property of Doxorubicin(6-maleimidocaproyl)hydrazone Edit

Chemical Property:

Boiling Point:°Cat760mmHg
PKA:7.38±0.60(Predicted)
Flash Point:°C
PSA：267.84000
Density:1.6g/cm³
LogP:1.41890
Solubility.:Soluble in DMSO
XLogP3:1.3
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:12
Exact Mass:750.27483741
Heavy Atom Count:54
Complexity:1510

Purity/Quality:

98% min ^*data from raw suppliers

DOXO-EMCH 98+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 23-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=NNC(=O)CCCCCN6C(=O)C=CC6=O)CO)O)N)O
Isomeric SMILES:CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(/C(=N/NC(=O)CCCCCN6C(=O)C=CC6=O)/CO)O)N)O
Recent ClinicalTrials:QUILT-2.024: Phase 2 Neoadjuvant, Consolidation, and Adjuvant Combination NANT Immunotherapy Versus Standard of Care in Subjects With Resectable Non-small Cell Lung Cancer
Recent EU Clinical Trials:A Multicenter, Randomized, Open-Label Phase 2b Study to Investigate the Efficacy and Safety of Aldoxorubicin Compared to Topotecan in Subjects with Metastatic Small Cell Lung Cancer Who Either Relapsed or Were Refractory to Prior Chemotherapy
Uses Doxorubicin-hydrazone-caproyl-maleimide is an albumin-binding prodrug of doxorubicin and a promising clinical candidate for the treatment of a broad range of solid tumors

Technology Process of Doxorubicin(6-maleimidocaproyl)hydrazone

There total 3 articles about Doxorubicin(6-maleimidocaproyl)hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%