1-(3-methoxy-4-methylphenyl)-2-aminopropane

Base Information

• Chemical Name: 1-(3-methoxy-4-methylphenyl)-2-aminopropane
• CAS No.: 87179-33-7
• Molecular Formula: C₁₁H₁₇NO
• Molecular Weight: 179.262
• Mol file: 87179-33-7.mol

Synonyms:

Chemical Property of 1-(3-methoxy-4-methylphenyl)-2-aminopropane

Chemical Property:

• Boiling Point: 271.8°Cat760mmHg
• Flash Point: 112.4°C
• PSA: 35.25000
• Density: 0.979g/cm³
• LogP: 2.59360

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(3-methoxy-4-methylphenyl)-2-aminopropane

There total 12 articles about 1-(3-methoxy-4-methylphenyl)-2-aminopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methoxy-1-methyl-4-[2-nitroprop-1-enyl]benzene (27571-99-9) → 1-(3-methoxy-4-methyl-phenyl)propan-2-amine (24160-29-0,87179-33-7)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1021/jm00256a016

Reference yield:

3-methoxy-4-methylbenzaldehyde (24973-22-6) → 1-(3-methoxy-4-methyl-phenyl)propan-2-amine (24160-29-0,87179-33-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 83.5 percent / ammonium acetate / 2.5 h / Heating

2: LiAlH₄ / diethyl ether / 2.5 h / Heating

With ammonium acetate; lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1021/jm00109a020

Reference yield:

1-(3-methoxy-4-methylphenyl)-2-nitropropene (132980-18-8) → 1-(3-methoxy-4-methyl-phenyl)propan-2-amine (24160-29-0,87179-33-7)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 2.5h; Heating;

DOI:10.1021/jm00109a020

upstream raw materials:

2-methoxy-1-methyl-4-[2-nitroprop-1-enyl]benzene

1-(3-methoxy-4-methylphenyl)-2-nitropropene

1-(3-methoxy-4-methylphenyl)-2-propanone

Nitroethane

Refernces

• 1、 -. "NOVEL DIHYDROQUINOLIZINONES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION". Page/Page column 125. . Retrieved 2015/09/23.
• 2、 Valenta,Protiva. "Synthesis of the 3 hydroxy 4 methyl derivative of amphetamine". . p. 2240 - 2245. Retrieved 2007/10/05.