2-BROMO-1,1,2-TRIFLUOROETHYL ETHYL ETHER

Base Information

• Chemical Name: 2-BROMO-1,1,2-TRIFLUOROETHYL ETHYL ETHER
• CAS No.: 380-78-9
• Molecular Formula: C4H6 Br F3 O
• Molecular Weight: 206.99
• Hs Code.: 2909199090
• Mol file: 380-78-9.mol

Synonyms:Ether,2-bromo-1,1,2-trifluoroethyl ethyl (6CI,8CI);2-Bromo-1-ethoxy-1,1,2-trifluoroethane

Chemical Property of 2-BROMO-1,1,2-TRIFLUOROETHYL ETHYL ETHER

Chemical Property:

• Refractive Index: 1.4000 (estimate)
• Boiling Point: 114.4°Cat760mmHg
• Flash Point: 23.9°C
• PSA: 9.23000
• Density: 1.581g/cm³
• LogP: 2.30620

Purity/Quality:

98%min ^*data from raw suppliers

2-Bromo-1,1,2-trifluoroethylEthylEther ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

Useful:

Technology Process of 2-BROMO-1,1,2-TRIFLUOROETHYL ETHYL ETHER

There total 3 articles about 2-BROMO-1,1,2-TRIFLUOROETHYL ETHYL ETHER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

ethanol (64-17-5) + 1-bromo-1,2,2-trifluoroethene (598-73-2,55157-25-0) → 1-ethoxy-1,1,2-trifluoro-2-bromoethane (380-78-9)

Guidance literature:

ethanol; With sodium; at 20 ℃; for 0.666667h;

1-bromo-1,2,2-trifluoroethene; In ethanol; Further stages.;

DOI:10.1002/jccs.200700107

Reference yield:

1-bromo-1,2,2-trifluoroethene (598-73-2,55157-25-0) + sodium ethanolate (141-52-6) → 1-ethoxy-1,1,2-trifluoro-2-bromoethane (380-78-9)

Guidance literature:

With ethanol;

DOI:10.1021/jo01105a608 DOI:10.1039/jr9520004259

Reference yield:

1-bromo-1,2,2-trifluoroethene (598-73-2,55157-25-0) + ethanolate (16331-64-9) → 1-ethoxy-1,1,2-trifluoro-2-bromoethane (380-78-9) + 1,1-Dibromo-2-ethoxy-1,2,2-trifluoro-ethane + (E)-1-Bromo-2-ethoxy-1,2-difluoro-ethene + (Z)-1-Bromo-2-ethoxy-1,2-difluoro-ethene

Guidance literature:

In tetrahydrofuran; for 4h; Yields of byproduct given; Ambient temperature;

DOI:10.1016/S0022-1139(00)81976-4

upstream raw materials:

ethanol

1-bromo-1,2,2-trifluoroethene

sodium ethanolate

ethanolate

Downstream raw materials:

ethyl bromofluoroacetate

Refernces

• 1、 Jiang, Xi-Kui,Ji, Guo-Znen,Shi,Yi-Qun. "OBSERVATION OF A COMPETITIVE PATH IN THE NUCLEOPHILIC ADDITION OF FLUOROOLEFINS: THE BROMOPHILIC REACTION OF THE ADDUCT CARBANOIN INTERMEDIATE". . p. 405 - 418. Retrieved 2007/10/02.