Betulone

Base Information

• Chemical Name: Betulone
• CAS No.: 7020-34-0
• Molecular Formula: C₃₀H₄₈O₂
• Molecular Weight: 440.71
• Mol file: 7020-34-0.mol

Synonyms:

Chemical Property of Betulone

Chemical Property:

Purity/Quality:

≥98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Betulone

There total 8 articles about Betulone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

betulin (473-98-3) → betulonic aldehyde (4439-98-9) + betulinic aldehyde (13159-28-9,92594-07-5) + betulone (7020-34-0)

Guidance literature:

With potassium dichromate; sulfuric acid; tetrabutylammomium bromide; In benzene; at 20 ℃; for 12h; Further Variations:; Reagents; Solvents; reaction times; Product distribution;

DOI:10.1023/A:1015733832373

Reference yield: 27.0%

betulin (473-98-3) → betulonic aldehyde (4439-98-9) + Betulinic acid (472-15-1) + betulone (7020-34-0)

Guidance literature:

With synthetic air; In 1,3,5-trimethyl-benzene; at 140 ℃; for 6h; under 760.051 Torr; Catalytic behavior;

DOI:10.1016/j.cattod.2020.07.051

Reference yield: 12.8%

betulin (473-98-3) → betulinic aldehyde (13159-28-9,92594-07-5) + betulone (7020-34-0) + betulonic aldehyde

Guidance literature:

In 1,3,5-trimethyl-benzene; at 140 ℃; for 4h; Reagent/catalyst;

DOI:10.1007/s10562-018-02649-8

upstream raw materials:

betulin

p-benzoquinone

aluminum tri-tert-butoxide

benzene

Downstream raw materials:

betulonic acid

betulonic aldehyde

Betulinic acid

C₄₇H₆₆N₂O₂

Refernces

• 1、 Kolobova, Ekaterina N.,Pakrieva, Ekaterina G.,Carabineiro, Sónia A. C.,Bogdanchikova, Nina,Kharlanov, Andrey N.,Kazantsev, Sergey O.,Hemming, Jarl,M?ki-Arvela, P?ivi,Pestryakov, Alexey N.,Murzin, Dmitry Yu.. "Oxidation of a wood extractive betulin to biologically active oxo-derivatives using supported gold catalysts". . p. 3370 - 3382. Retrieved 2019/06/24.
• 2、 Pichette, Andre,Liu, Hongyan,Roy, Christian,Tanguay, Steve,Simard, Francois,Lavoie, Serge. "Selective oxidation of betulin for the preparation of betulinic acid, an antitumoral compound". . p. 3925 - 3937. Retrieved 2007/10/03.