Technology Process of 1-[2-(1H-indol-3-yl)ethyl]-3-(methoxycarbonyl)pyridinium
There total 5 articles about 1-[2-(1H-indol-3-yl)ethyl]-3-(methoxycarbonyl)pyridinium which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
neat (no solvent);
at 70 ℃;
for 8h;
Inert atmosphere;
DOI:10.3987/COM-17-13822
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: diethyl ether / 6 h / 0 - 20 °C / Inert atmosphere
1.2: 0 °C / Inert atmosphere
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere
3.1: triphenylphosphine; carbon tetrabromide / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere
4.1: neat (no solvent) / 8 h / 70 °C / Inert atmosphere
With
lithium aluminium tetrahydride; carbon tetrabromide; triphenylphosphine;
In
tetrahydrofuran; diethyl ether; dichloromethane;
1.1: |Friedel-Crafts Acylation;
DOI:10.3987/COM-17-13822
- Guidance literature:
-
Multi-step reaction with 3 steps
1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere
2: triphenylphosphine; carbon tetrabromide / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere
3: neat (no solvent) / 8 h / 70 °C / Inert atmosphere
With
lithium aluminium tetrahydride; carbon tetrabromide; triphenylphosphine;
In
tetrahydrofuran; dichloromethane;
DOI:10.3987/COM-17-13822