2-BROMO-1,3-INDANEDIONE

Base Information

• Chemical Name: 2-BROMO-1,3-INDANEDIONE
• CAS No.: 7319-63-3
• Molecular Formula: C9H5BrO2
• Molecular Weight: 225.041
• Hs Code.: 2914700090
• Mol file: 7319-63-3.mol

Synonyms:2-Bromo-1,3-indanedione;

Chemical Property of 2-BROMO-1,3-INDANEDIONE

Chemical Property:

• Vapor Pressure: 0.000124mmHg at 25°C
• Melting Point: 118-120 °C
• Refractive Index: 1.66
• Boiling Point: 334.9 °C at 760 mmHg
• PKA: 5.17±0.20(Predicted)
• Flash Point: 139.8 °C
• PSA: 34.14000
• Density: 1.787 g/cm³
• LogP: 1.82910

Purity/Quality:

99.5% ^*data from raw suppliers

2-Bromoindane-1,3-dione 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: 2-Bromo-1,3-indandione was used in the synthesis of 2-benzylthio-1,3-indandione.

Technology Process of 2-BROMO-1,3-INDANEDIONE

There total 11 articles about 2-BROMO-1,3-INDANEDIONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1H-indene-1,3(2H)-dione (606-23-5) → 2-bromo-indan-1,3-dione (7319-63-3)

Guidance literature:

With hydrogenchloride; dihydrogen peroxide; potassium bromide; In toluene; at 20 ℃; for 0.5h;

DOI:10.1055/s-2006-948207

Reference yield: 80.0%

1H-indene-1,3(2H)-dione (606-23-5) → 2-bromo-indan-1,3-dione (7319-63-3) + 2,2-dibromo-indan-1,3-dione (1685-97-8)

Guidance literature:

With Oxone; ammonium bromide; In methanol; at 20 ℃; for 1h; regioselective reaction;

DOI:10.1016/j.tetlet.2011.11.011

Reference yield:

2,2-dibromo-1-hydroxy-3-oxo-indan-1-carboxylic acid → carbon dioxide (124-38-9,18923-20-1) + 2-bromo-indan-1,3-dione (7319-63-3) + hydrogen bromide (10035-10-6,12258-64-9)

Guidance literature:

upstream raw materials:

ethanol

2,3-dibromoinden-1-one

2,2-dibromo-indan-1,3-dione

2-bromo-1,3-dioxo-indan-2-carboxylic acid ethyl ester

Downstream raw materials:

1H-indene-1,3(2H)-dione

2,2-dibromo-indan-1,3-dione

indan-1,2,3-trione-2-(4-nitro-phenylhydrazone)

1,3-dimethyl-5-phenyl-1H-indeno[2′,1′:5,6]pyrido[2,3-d]pyrimidine-2,4,6(3H)-trione

Refernces

• 1、 Elshafei,Ahmed, Eman A.,Abd El-Raheem. "Synthesis of some new fused and spiro heterocyclic compounds under phase transfer catalysis (PTC) conditions". . p. 485 - 494. Retrieved 2016/08/19.
• 2、 Dabholkar, Vijay V.,Patil, Sunil R.,Pandey, Rajesh V.. "Dimethylformamide catalyzed synthesis of novel heterocycles - Their characterization and antimicrobial evaluation". . p. 403 - 407. Retrieved 2013/06/26.