5-Isoxazolidinecarboxylic acid

Base Information

• Chemical Name: 5-Isoxazolidinecarboxylic acid
• CAS No.: 36839-09-5
• Molecular Formula: C₄H₇NO₃
• Molecular Weight: 117.104
• DSSTox Substance ID: DTXSID60958038
• Mol file: 36839-09-5.mol

Synonyms:(+-)-isomer of 5-oxaproline;5-isoxazolidinecarboxylic acid;5-oxaproline

Chemical Property of 5-Isoxazolidinecarboxylic acid

Chemical Property:

• Vapor Pressure: 0.00855mmHg at 25°C
• Boiling Point: 246.9°Cat760mmHg
• Flash Point: 103.1°C
• PSA: 58.56000
• Density: 1.33g/cm³
• LogP: -0.30670
• XLogP3: -2.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 117.042593085
• Heavy Atom Count: 8
• Complexity: 104

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CNOC1C(=O)O

Technology Process of 5-Isoxazolidinecarboxylic acid

There total 1 articles about 5-Isoxazolidinecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

di-tert-butyl isoxazolidine-2,5-dicarboxylate → isoxazolidine-5-carboxylic acid (36839-09-5)

Guidance literature:

With trifluoroacetic acid; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1055/s-0036-1588480

Refernces