3'-Deoxytubercidin

Base Information Edit

Chemical Name:3'-Deoxytubercidin
CAS No.:40725-89-1
Molecular Formula:C11H14N4O3
Molecular Weight:250.257
Hs Code.:
NSC Number:124154
DSSTox Substance ID:DTXSID30961150
ChEMBL ID:CHEMBL141709
Mol file:40725-89-1.mol

Synonyms:7-CH-5'-AMP SODIUM SALT;5'-deoxy-5'-(methylthio)tubercidin;tubercidin 5'-phosphate;tubercidin-5-monophosphate;3'-deoxytubercidin;7-deaza-[5']adenylic acid;TUBERCIDIN-5'-O-MONOPHOSPHATE SODIUM SALT;7-DEAZAADENOSINE-5'-O-MONOPHOSPHATE SODIUM SALT;Tubercidin-5'-phosphat;

Suppliers and Price of 3'-Deoxytubercidin

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 3'-Deoxytubercidin Edit

Chemical Property:

Vapor Pressure:2.62E-15mmHg at 25°C
Boiling Point:601.3°Cat760mmHg
Flash Point:317.5°C
PSA：106.42000
Density:1.75g/cm³
LogP:0.23540
XLogP3:-0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:250.10659032
Heavy Atom Count:18
Complexity:306

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(OC(C1O)N2C=CC3=C(N=CN=C32)N)CO

Technology Process of 3'-Deoxytubercidin

There total 16 articles about 3'-Deoxytubercidin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 4-amino-5-bromo-N7-(3'-deoxy-5'-O-t-butyldimethylsilyl)-β-D-ribofuranosylpyrrolo[2,3-d]pyrimidine

: 40725-89-1
4-amino-N7-(3'-deoxy-β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine

Guidance literature:: With trifluoroacetic acid; In water; at 20 ℃;

Reference yield: 43.0%

: 69-33-0
tubercidin

: 40725-89-1
4-amino-N7-(3'-deoxy-β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine

Guidance literature:: tubercidin; With 2-acetoxy-2-methylpropanoyl chloride; sodium iodide; In acetonitrile; for 1.5h;

With palladium on activated charcoal; hydrogen; In methanol;

With ammonia; In methanol;

Reference yield:

: 582-52-5
1,2:5,6-di-O-isopropylidene-α-D-glucofuranose

: 40725-89-1
4-amino-N7-(3'-deoxy-β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine

Guidance literature:: Multi-step reaction with 9 steps

1.1: 1H-imidazole; sodium hydride / tetrahydrofuran; mineral oil / 0.33 h

1.2: 0.5 h

2.1: acetic acid / water

2.2: 0.5 h / 0 °C

2.3: 0 °C

3.1: triethylamine; dmap / dichloromethane / 0 °C / Inert atmosphere

4.1: hydrogenchloride / water / 50 - 55 °C

4.2: 0 - 20 °C

5.1: acetic acid; sulfuric acid / Cooling with ice

6.1: BSA / acetonitrile / 0.17 h / Inert atmosphere

6.2: 0.25 h / 20 °C

7.1: ammonia / methanol / 130 °C

8.1: 1H-imidazole / N,N-dimethyl-formamide / 0 - 20 °C

9.1: trifluoroacetic acid / water / 20 °C

With 1H-imidazole; hydrogenchloride; dmap; sulfuric acid; ammonia; sodium hydride; acetic acid; triethylamine; trifluoroacetic acid; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; mineral oil; 6.1: |Vorbrueggen Nucleoside Synthesis / 6.2: |Vorbrueggen Nucleoside Synthesis;